Management of Scleritis in Older Adults.

IF 3.4 3区 医学 Q2 GERIATRICS & GERONTOLOGY Drugs & Aging Pub Date : 2024-04-01 Epub Date: 2024-03-05 DOI:10.1007/s40266-024-01105-0
Laura Butler, Oren Tomkins-Netzer, Or Reiser, Rachael L Niederer
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Abstract

Scleritis, an inflammatory disease of the eye affecting scleral tissue, presents unique challenges in the older adult population. Unlike their younger counterparts, older individuals manifest a distinct spectrum of the disease with different underlying etiologies, co-morbidities, altered immune function, and an increased risk of systemic side effects from medication choices. Addressing these complexities necessitates a comprehensive and multidisciplinary approach. Treatment of choice will depend on any underlying cause but generally involves non-steroidal anti-inflammatory drugs, systemic or local corticosteroids, and potentially disease-modifying anti-rheumatic drugs. Utilization of these therapeutic agents in older adults warrants careful consideration because of their potential side-effect profiles. This article critically examines the specific concerns for the use of these drugs in older patients and reviews the existing literature on their use in this specific cohort.

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老年人巩膜炎的管理。
巩膜炎是一种影响巩膜组织的眼部炎症性疾病,给老年人群带来了独特的挑战。与年轻人不同,老年人表现出不同的疾病谱,有不同的潜在病因、并发症、免疫功能改变以及因药物选择而增加的全身副作用风险。要解决这些复杂问题,就必须采取全面的多学科方法。治疗方法的选择取决于任何潜在的病因,但一般包括非甾体类抗炎药、全身或局部皮质类固醇激素以及潜在的疾病修饰抗风湿药。由于其潜在的副作用,在老年人中使用这些治疗药物需要慎重考虑。本文对老年患者使用这些药物的具体问题进行了认真研究,并回顾了在这一特定人群中使用这些药物的现有文献。
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来源期刊
Drugs & Aging
Drugs & Aging 医学-老年医学
CiteScore
5.50
自引率
7.10%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Drugs & Aging delivers essential information on the most important aspects of drug therapy to professionals involved in the care of the elderly. The journal addresses in a timely way the major issues relating to drug therapy in older adults including: the management of specific diseases, particularly those associated with aging, age-related physiological changes impacting drug therapy, drug utilization and prescribing in the elderly, polypharmacy and drug interactions.
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