Workforce readiness for pharmacogenomics and key elements for sustainment within the Veterans Health Administration.

IF 1.9 4区医学 Q3 PHARMACOLOGY & PHARMACY Pharmacogenomics Pub Date : 2024-02-01 Epub Date: 2024-03-05 DOI:10.2217/pgs-2023-0193

Rebekah Ryanne Wu, Richelle Benevent, Nina R Sperber, Jill S Bates, Daniel Villa, Dilhan Weeraratne, Timothy A Burrell, Deepak Voora

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Abstract

Aim: Understanding barriers and facilitators to pharmacogenomics (PGx) implementation and how to structure a clinical program with the Veterans Health Administration (VA). Materials & methods: Healthcare provider (HCP) survey at 20 VA facilities assessing PGx knowledge/acceptance and qualitative interviews to understand how best to design and sustain a national program. Results: 186 (12% response rate) surveyed believed PGx informs drug efficacy (74.7%) and adverse events (71.0%). Low confidence in knowledge (43.0%) and ability to implement (35.4-43.5%). 23 (60.5% response rate) interviewees supported a nationally program to oversee VA education, consultation and IT resources. Prescribing HCPs should be directing local activities. Conclusion: HCPs recognize PGx value but are not prepared to implement. Healthcare systems should build system-wide programs for implementation education and support.

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退伍军人健康管理局内药物基因组学的人员准备情况和持续发展的关键因素。

目的：了解药物基因组学 (PGx) 实施的障碍和促进因素，以及如何与退伍军人健康管理局 (VA) 一起制定临床计划。材料与方法：对退伍军人健康管理局的 20 家机构进行医疗保健提供者 (HCP) 调查，评估 PGx 知识/接受度，并进行定性访谈，以了解如何以最佳方式设计和维持一项全国性计划。结果：接受调查的 186 名医护人员（回复率为 12%）认为 PGx 可为药物疗效（74.7%）和不良事件（71.0%）提供信息。对知识（43.0%）和实施能力（35.4-43.5%）的信心不足。23 位受访者（回复率 60.5%）支持在全国范围内开展一项计划，以监督退伍军人事务部的教育、咨询和 IT 资源。开处方的保健医生应指导当地的活动。结论：医疗保健人员认识到 PGx 的价值，但尚未做好实施的准备。医疗保健系统应建立全系统的实施教育和支持计划。

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来源期刊

Pharmacogenomics 医学-药学

CiteScore

3.40

自引率

9.50%

发文量

审稿时长

4-8 weeks

期刊介绍： Pharmacogenomics (ISSN 1462-2416) is a peer-reviewed journal presenting reviews and reports by the researchers and decision-makers closely involved in this rapidly developing area. Key objectives are to provide the community with an essential resource for keeping abreast of the latest developments in all areas of this exciting field. Pharmacogenomics is the leading source of commentary and analysis, bringing you the highest quality expert analyses from corporate and academic opinion leaders in the field.