Prevention, diagnosis, and treatment of urolithiasis in geriatric patients - differences, similarities and caveats in comparison to the general population.

IF 2.2 3区 医学 Q2 UROLOGY & NEPHROLOGY Current Opinion in Urology Pub Date : 2024-05-01 Epub Date: 2024-03-05 DOI:10.1097/MOU.0000000000001173
Tarek A Schrag, Danielle Diarra, Julian Veser
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Abstract

Purpose of review: Purpose of the review is to address management and prevention of urolithiasis in elderly patients examining the dynamic interplay between general measures, dietary adjustments, lifestyle modifications, and targeted pharmacological and/ or surgical interventions. The goal is to provide understanding of the evolving strategies required for effective urolithiasis prevention in the geriatric population.

Recent findings: Age-specific diagnostic considerations are necessary because urolithiasis in the elderly population is characterized by bigger stones, greater peri-operative risks, and heightened symptom severity. When comorbidities are present, conservative treatments - especially analgesia - provide difficulties. Surgical procedures prove to be safe and effective, with complication rates and practical application comparable to younger cohorts. Prevention approaches that include lifestyle changes and the investigation of novel pharmaceutical options such as sodium-dependent glucose co-transporter 2 (SGLT-2)-inhibitors are promising in the management of urolithiasis in the elderly population.

Summary: Our review offers a thorough investigation of urolithiasis in the elderly population, elucidating distinct clinical manifestations, complex diagnostic issues, and treatment implications. The safety and effectiveness of ureteroscopy in older patients, as well as the possible prophylactic function of SGLT-2-I, offer crucial insights for clinicians. Subsequent studies are necessary to enhance age-specific therapies, addressing the distinct obstacles presented by urolithiasis in the elderly population within this rapidly growing demographic.

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老年病人泌尿系统结石的预防、诊断和治疗--与普通人群的差异、相似之处和注意事项。
综述的目的:综述的目的是探讨老年患者尿路结石的管理和预防,研究一般措施、饮食调整、生活方式改变以及有针对性的药物和/或手术干预之间的动态相互作用。目的是让人们了解有效预防老年尿路结石所需的不断变化的策略:最新研究结果:由于老年人尿路结石的特点是结石更大、围手术期风险更高、症状更严重,因此有必要考虑特定年龄段的诊断。当合并症出现时,保守治疗--尤其是镇痛--会带来困难。事实证明,手术治疗安全有效,并发症发生率和实际应用与年轻群体相当。包括改变生活方式在内的预防方法以及钠依赖性葡萄糖共转运体 2(SGLT-2)抑制剂等新型药物的研究在治疗老年人尿路结石方面前景广阔。老年患者接受输尿管镜检查的安全性和有效性,以及 SGLT-2-I 可能具有的预防功能,都为临床医生提供了重要的启示。有必要开展后续研究,以加强针对特定年龄段的疗法,解决在这一快速增长的人口群体中老年人尿路结石所带来的独特障碍。
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来源期刊
Current Opinion in Urology
Current Opinion in Urology 医学-泌尿学与肾脏学
CiteScore
5.00
自引率
4.00%
发文量
140
审稿时长
6-12 weeks
期刊介绍: ​​​​​​​​Current Opinion in Urology delivers a broad-based perspective on the most recent and most exciting developments in urology from across the world. Published bimonthly and featuring ten key topics – including focuses on prostate cancer, bladder cancer and minimally invasive urology – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.
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