Wenjuan Li , Xiao Li , Hailong Hong , Ruijun Xie , Ning Zhu
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引用次数: 0
Abstract
An effective, green and eco-friendly method was developed to synthesize 1H-benzimidazole under microwave irradiation. The reactions of substituted o-phenylenediamine with DMF were efficiently promoted by butanoic acid, and the desired product 1H-benzimidazole derivatives were obtained in good to excellent yields. Compared with the conventional heating method, microwave irradiation significantly reduced the reaction time and improved the yields of the target products.
期刊介绍：
Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.
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