Duration of Untreated Illness in Obsessive-Compulsive Disorder and its Associated Factors.

Psychopharmacology bulletin Pub Date : 2024-03-04
Anas Ibn Auf, Abdelgadir Osman
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Abstract

Introduction: The period before effective treatment is administered, is known as the duration of untreated illness (DUI). It has been found to relate to prognoses and sensitivity to treatment. The DUI is yet to be fully investigated in relation to obsessive-compulsive disorder (OCD).

Method: The present study examined a sample of 89 patients who presented with OCD over a span of two years and who were treated at a clinic in Khartoum, the capital city of Sudan. We examined the mean DUI before the patients received an effective psychiatric intervention. We also gauged different sociodemographic and clinical presentations associated with DUI.

Results: The sample comprised 55 male (61.8%) and 34 female patients (38.2%). Around 75% were single (N = 67); 34 participants (38.2%) were students; 28 (31.5%) were employed; and 27 (30.3%) were unemployed. The mean age of the participants was 27.12 years (SD ± 8.72) and the mean age at the first onset of the disorder was 21.72 years (SD ± 7.51). The mean of DUI was 5.41 years (SD ± 5.53). There was no significant difference in DUI in respect of age or gender. It was significantly longer in unemployed patients (7.59 years ± 5.93) than in employed (6.37 years ± 6.64) or students (2.88 years ± 2.59); p = 0.002. Married OCD patients had a longer DUI than single patients.

Conclusion: The present study highlighted a considerable delay before OCD patients received effective treatment. Although many intractable cultural and socioeconomic factors were tested, the strongest associations were found to be unemployment and marital status.

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强迫症未治疗的持续时间及其相关因素。
导言:在进行有效治疗之前的这段时间被称为未治疗病程(DUI)。研究发现,这与预后和对治疗的敏感性有关。目前尚未对强迫症(OCD)的未治疗病程进行全面研究:本研究对苏丹首都喀土穆一家诊所在两年内治疗的 89 名强迫症患者进行了抽样调查。我们调查了患者在接受有效精神干预之前的平均酒驾率。我们还评估了与酒驾相关的不同社会人口学和临床表现:样本包括 55 名男性患者(61.8%)和 34 名女性患者(38.2%)。约 75% 为单身(N = 67);34 名参与者(38.2%)为学生;28 名(31.5%)为在职者;27 名(30.3%)为失业者。参与者的平均年龄为 27.12 岁(SD ± 8.72),首次发病的平均年龄为 21.72 岁(SD ± 7.51)。酒后驾车的平均年龄为 5.41 岁(标准差 ± 5.53)。年龄和性别在酒驾方面没有明显差异。失业患者的 DUI(7.59 年 ± 5.93)明显长于就业者(6.37 年 ± 6.64)或学生(2.88 年 ± 2.59);P = 0.002。已婚强迫症患者的 DUI 时间长于单身患者:本研究强调了强迫症患者在接受有效治疗之前存在相当长的延迟。尽管对许多难以解决的文化和社会经济因素进行了测试,但发现与失业和婚姻状况的关系最为密切。
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