Immunogenic Xist ribonucleoproteins drive sex-biased autoimmunity

IF 29.4 1区医学 Q1 RHEUMATOLOGY Nature Reviews Rheumatology Pub Date : 2024-03-07 DOI:10.1038/s41584-024-01101-z

Jessica McHugh

引用次数: 0

Abstract

Ribonucleoprotein complexes containing Xist, a long non-coding RNA involved in X chromosome inactivation, are immunogenic and promote autoimmune responses.

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具有免疫原性的 Xist 核糖核蛋白可驱动具有性别差异的自身免疫。

核糖核蛋白复合物含有 Xist（一种参与 X 染色体失活的长非编码 RNA），具有免疫原性，可促进自身免疫反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Rheumatology 医学-风湿病学

CiteScore

29.90

自引率

0.90%

发文量

137

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Rheumatology is part of the Nature Reviews portfolio of journals. The journal scope covers the entire spectrum of rheumatology research. We ensure that our articles are accessible to the widest possible audience.

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