Hepatocellular carcinoma and upper gastrointestinal bleeding

IF 3.7 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Annals of hepatology Pub Date : 2024-02-01 DOI:10.1016/j.aohep.2024.101389
Ricardo J. Ortega-García, Gaspar Herrera-Aranda, Francisco Rodríguez-Illana, Estaban Figueroa-Martínez, Josefina Álvaro-Vásquez, Roger Juárez-Puc, Janet Mayren-Aguilar
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Abstract

Introduction and Objectives

Hepatocellular carcinoma represents the most frequent malignant tumor of the liver, being the 5th most frequent cancer in men and the 7th in women worldwide; it is the 3rd cause of death from cancer in the world. To present a case of hepatocellular carcinoma presenting with gastrointestinal bleeding.

Materials and Patients

A 39-year-old female began her condition two days ago with the presence of hematemesis, accompanied by nausea, asthenia, and adynamia. On examination, icteric conjunctivae, globose abdomen, with the presence of abdominal distension, grade I ascites. Edema in the lower limbs +. Liver ultrasound with liver nodular lesions, chronic lithiasic cholecystitis, and free fluid in the abdominopelvic cavity. A simple and contrasted CT scan of the abdomen is requested with the presence of tumor activity at the level of the liver, portal thrombosis, free fluid in the abdominal cavity, and marginal T12-L1 osteocytes.

Results

We proceeded to perform sclerotherapy of esophageal varices and ligatures. Later, alpha-fetoprotein was requested, which reports 3680 ng/ml. The diagnosis of hepatocarcinoma was established and he was referred to the oncology service.

Conclusions

The best results are obtained with multidisciplinary teams for the diagnosis and treatment of this disease.

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肝细胞癌和上消化道出血
导言和目的肝细胞癌是最常见的肝脏恶性肿瘤,在全球男性癌症发病率中占第 5 位,在女性癌症发病率中占第 7 位;在全球癌症死亡原因中占第 3 位。材料和患者一名 39 岁女性两天前开始出现吐血症状,并伴有恶心、气喘和乏力。经检查,她的眼结膜呈琥珀色,腹部呈球状,腹部胀大,有 I 级腹水。下肢水肿+。肝脏超声波检查显示肝脏结节性病变、慢性石胆囊炎和腹盆腔游离液体。如果肝脏水平存在肿瘤活动、门静脉血栓、腹腔内有游离液体以及边缘性 T12-L1 骨细胞,则需要进行腹部简易对比 CT 扫描。随后,我们要求检测甲胎蛋白,结果显示为 3680 ng/ml。最终确诊为肝癌,并将其转诊至肿瘤科。
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来源期刊
Annals of hepatology
Annals of hepatology 医学-胃肠肝病学
CiteScore
7.90
自引率
2.60%
发文量
183
审稿时长
4-8 weeks
期刊介绍: Annals of Hepatology publishes original research on the biology and diseases of the liver in both humans and experimental models. Contributions may be submitted as regular articles. The journal also publishes concise reviews of both basic and clinical topics.
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