Risk factors for electrical storms following percutaneous coronary intervention in patients with acute myocardial infarction: A meta-analysis.

0 MEDICINE, RESEARCH & EXPERIMENTAL Biomolecules & biomedicine Pub Date : 2024-09-06 DOI:10.17305/bb.2024.10274
Xiao Xiong, Qiang Ye, Yongquan Peng
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Abstract

Electrical storms (ESs) following percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI) patients pose a significant challenge, affecting prognostic outcomes and increasing mortality. This meta-analysis synthesized data from 11 studies involving 9,666 AMI patients to identify risk factors associated with ES following PCI. Our findings revealed an average ES incidence of 7.70%, with identified risk factors including low thrombolysis in myocardial infarction (TIMI) flow grades (0-1), elevated cardiac troponin I levels, persistent hypotension, reperfusion arrhythmias, the right coronary artery being the infarct-related artery, increased diameter of the infarct-related artery, renal dysfunction, elevated creatine kinase-MB, and bradycardia. Notably, the use of β-blockers was found to significantly reduce the risk of ES. The study underscores the importance of early identification and management of these risk factors in AMI patients undergoing PCI to prevent the occurrence of ES, highlighting the protective role of β-blockers. This research provides a foundation for future strategies aimed at reducing the incidence and improving the prognosis of ES in this patient population.

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急性心肌梗死患者经皮冠状动脉介入治疗后发生电风暴的风险因素:荟萃分析
急性心肌梗死(AMI)患者经皮冠状动脉介入治疗(PCI)后发生电风暴(ES)是一项重大挑战,会影响预后结果并增加死亡率。这项荟萃分析综合了 11 项研究的数据,涉及 9,666 名急性心肌梗死患者,以确定与 PCI 后发生电击相关的风险因素。我们的研究结果显示,ES 的平均发生率为 7.70%,已确定的风险因素包括心肌梗死溶栓(TIMI)血流分级低(0-1 级)、心肌肌钙蛋白 I 水平升高、持续低血压、再灌注心律失常、右冠状动脉为梗死相关动脉、梗死相关动脉直径增大、肾功能不全、肌酸激酶-MB 升高和心动过缓。值得注意的是,使用β-受体阻滞剂可显著降低ES风险。该研究强调了在接受 PCI 治疗的 AMI 患者中早期识别和管理这些风险因素对预防 ES 发生的重要性,并突出了 β 受体阻滞剂的保护作用。这项研究为未来旨在降低这类患者 ES 发生率和改善 ES 预后的策略奠定了基础。
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