Case report: CMV retinitis following local and systemic immunosuppression

Bryant A Menke, William Wagner, Helen Song, William Thomas, Natalia E. Castillo Almeida, Christopher D. Conrady, Steven Yeh
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Abstract

We report the case of a 71-year-old man who presented 2 years following renal transplantation with diffuse, unilateral cytomegalovirus retinitis five weeks after receiving an intravitreal dexamethasone implant device for the management of central retinal vein occlusion. Examination of the left eye showed diffuse retinal hemorrhages, attenuated and tortuous retinal vessels, and superior retinal whitening. The patient was successfully treated with serial intravitreal foscarnet injections and oral valganciclovir with disease regression observed by 12 weeks after presentation. The patient’s visual acuity and examination remained stable at 9-months follow-up.
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病例报告:局部和全身免疫抑制后的巨细胞病毒视网膜炎
我们报告了一例 71 岁男性患者的病例,他在肾移植术后 2 年,接受了用于治疗视网膜中央静脉闭塞的玻璃体内地塞米松植入装置 5 周后,出现弥漫性单侧巨细胞病毒视网膜炎。左眼检查显示弥漫性视网膜出血、视网膜血管衰减和迂曲,以及视网膜上部发白。患者接受了连续的玻璃体内福斯卡尼注射和口服缬更昔洛韦治疗,并在发病后12周观察到疾病消退。随访 9 个月后,患者的视力和检查结果保持稳定。
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