Follow-up of cognitive impairment and inflammatory profile in individuals with mild COVID-19

IF 2.9 4区 医学 Q3 IMMUNOLOGY Journal of neuroimmunology Pub Date : 2024-03-05 DOI:10.1016/j.jneuroim.2024.578327
Nathália Gualberto Souza-Silva , Daniela Valadão Rosa , Jonas Jardim de Paula , Roney Santos Coimbra , Débora Marques Miranda , Marco Aurélio Romano-Silva
{"title":"Follow-up of cognitive impairment and inflammatory profile in individuals with mild COVID-19","authors":"Nathália Gualberto Souza-Silva ,&nbsp;Daniela Valadão Rosa ,&nbsp;Jonas Jardim de Paula ,&nbsp;Roney Santos Coimbra ,&nbsp;Débora Marques Miranda ,&nbsp;Marco Aurélio Romano-Silva","doi":"10.1016/j.jneuroim.2024.578327","DOIUrl":null,"url":null,"abstract":"<div><p>Individuals who experience mild COVID-19 can suffer from long-lasting cognitive symptoms. Notably, 26% of these individuals experience difficulties with visuospatial abilities six months after infection. However, among those who initially exhibited visuoconstructive impairments, 66% showed improvement or complete reversal over time. Additionally, changes in cytokine levels, particularly CCL11, HGF, and CXCL10, were observed. These results suggest a potential link between ongoing cognitive issues and elevated levels of pro-inflammatory cytokines, which merits further investigation.</p></div>","PeriodicalId":16671,"journal":{"name":"Journal of neuroimmunology","volume":"389 ","pages":"Article 578327"},"PeriodicalIF":2.9000,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of neuroimmunology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165572824000456","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Individuals who experience mild COVID-19 can suffer from long-lasting cognitive symptoms. Notably, 26% of these individuals experience difficulties with visuospatial abilities six months after infection. However, among those who initially exhibited visuoconstructive impairments, 66% showed improvement or complete reversal over time. Additionally, changes in cytokine levels, particularly CCL11, HGF, and CXCL10, were observed. These results suggest a potential link between ongoing cognitive issues and elevated levels of pro-inflammatory cytokines, which merits further investigation.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
随访轻度 COVID-19 患者的认知障碍和炎症特征
轻度 COVID-19 感染者会出现长期的认知症状。值得注意的是,这些人中有 26% 在感染 6 个月后出现视觉空间能力障碍。然而,在最初表现出视觉结构障碍的人中,66%的人随着时间的推移症状有所改善或完全逆转。此外,还观察到细胞因子水平的变化,尤其是 CCL11、HGF 和 CXCL10。这些结果表明,持续的认知问题与促炎细胞因子水平升高之间存在潜在联系,值得进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Journal of neuroimmunology
Journal of neuroimmunology 医学-免疫学
CiteScore
6.10
自引率
3.00%
发文量
154
审稿时长
37 days
期刊介绍: The Journal of Neuroimmunology affords a forum for the publication of works applying immunologic methodology to the furtherance of the neurological sciences. Studies on all branches of the neurosciences, particularly fundamental and applied neurobiology, neurology, neuropathology, neurochemistry, neurovirology, neuroendocrinology, neuromuscular research, neuropharmacology and psychology, which involve either immunologic methodology (e.g. immunocytochemistry) or fundamental immunology (e.g. antibody and lymphocyte assays), are considered for publication.
期刊最新文献
Correspondence: Electroconvulsive therapy in N-methyl-D-aspartate receptor encephalitis. Pure spinal multiple sclerosis: A case series of a possible new entity. A 7-year-old with new-onset seizures, behavior disturbance, and encephalitis. Corrigendum to "Elevated frequencies of activated memory B cells in multiple sclerosis are reset to healthy control levels are B cell depletion with Ocrelizumab" [J. Neuroimmunol. 339:578502 (2024)]. Vitamin C co-administration with artemether-lumefantrine abrogates chronic stress exacerbated Plasmodium berghei-induced sickness behaviour, inflammatory and oxidative stress responses in mice.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1