Comparative Analysis of Abnormal Pregnancy Between Non-Diabetic Pregnant Women and Diabetic Pregnant Women by Using Nanobubbles-Based Ultrasound Images

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-03-01 DOI:10.1166/jbn.2024.3510
Jue Wu, Jun Liu, Hongping Ou, Zheyu Hao
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Abstract

Objective: ultrasound imaging based on nanobubbles was used as the examination method in this study. Abdominal examination was performed on patients with and without diabetes during pregnancy, and the examination data between patients in different groups were compared and analyzed. Methods: 74 pregnant women were selected and enrolled in this study. Thirty-five pregnant women with diabetes were enrolled in the experimental group (Exp group) and 39 pregnant women without diabetes were assigned to the control group (Ctrl group). Results: there were no significant differences in fetal abdominal circumference, femoral length, and biparietal diameter between the two groups. The liver length and head circumference in the Exp group were higher based on the Ctrl group, with a statistical significance. Moreover, the occurrence probability of abnormal fetal growth and development indexes in the Exp group was higher and exhibited a statistical significance to that in the Ctrl group. Conclusion: patients with diabetes were more likely to have abnormal pregnancies. It is necessary to adopt color examination for clinical screening of diabetic pregnant women, so that the life safety of pregnant women and fetus can be guaranteed, reflecting the good application prospect of ultrasound examination.
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利用基于纳米气泡的超声波图像对非糖尿病孕妇和糖尿病孕妇的异常妊娠进行比较分析
目的:本研究采用基于纳米气泡的超声成像作为检查方法。对妊娠期糖尿病患者和非糖尿病患者进行腹部检查,并对不同组别患者的检查数据进行比较和分析。方法:本研究选取了 74 名孕妇。实验组(Exp 组)为 35 名糖尿病孕妇,对照组(Ctrl 组)为 39 名非糖尿病孕妇。结果:两组孕妇的胎儿腹围、股骨长度和双顶径无明显差异。Exp组的肝长和头围比Ctrl组高,有统计学意义。此外,Exp 组胎儿生长发育指标异常的发生概率比 Ctrl 组高,且有统计学意义。结论:糖尿病患者更容易出现异常妊娠。临床上有必要采用彩超检查对糖尿病孕妇进行筛查,从而保障孕妇和胎儿的生命安全,体现了超声检查良好的应用前景。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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