Dietary Magnesium Intake Is Inversely Associated With Ulcerative Colitis: A Case-Control Study.

IF 1.8 Q3 GASTROENTEROLOGY & HEPATOLOGY Crohn's & Colitis 360 Pub Date : 2024-02-21 eCollection Date: 2024-01-01 DOI:10.1093/crocol/otae009
Omid Sadeghi, Zeinab Khademi, Parvane Saneei, Ammar Hassanzadeh-Keshteli, Hamed Daghaghzadeh, Hamid Tavakkoli, Peyman Adibi, Ahmad Esmaillzadeh
{"title":"Dietary Magnesium Intake Is Inversely Associated With Ulcerative Colitis: A Case-Control Study.","authors":"Omid Sadeghi, Zeinab Khademi, Parvane Saneei, Ammar Hassanzadeh-Keshteli, Hamed Daghaghzadeh, Hamid Tavakkoli, Peyman Adibi, Ahmad Esmaillzadeh","doi":"10.1093/crocol/otae009","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Ulcerative colitis (UC) causes long-lasting inflammation and ulcers in the gut. Limited observational data are available linking dietary magnesium intake and UC. In the present study, we aimed to investigate the association between dietary magnesium intake and UC in adults.</p><p><strong>Methods: </strong>The current population-based case-control study was performed on 109 UC patients and 218 age (±2 years) and sex-matched controls. The diagnosis of UC was made according to the standard criteria by a gastroenterology specialist. Dietary intakes were assessed using a validated self-administrated 106-item dish-based Food Frequency Questionnaire (FFQ). We also used a pretested questionnaire to collect data on potential confounders.</p><p><strong>Results: </strong>Individuals in the top tertile of magnesium intake were less likely to have UC compared with those in the bottom tertile. A significant inverse relationship was found between dietary magnesium intake and UC (odds ratio [OR]: 0.32, 95% confidence interval [CI]: 0.18-0.59) in the crude model. This relationship was also observed when we took several potential confounding into account (OR: 0.30, 95% CI: 0.14-0.68).</p><p><strong>Conclusions: </strong>Adherence to a magnesium-rich diet may have a role in preventing UC. However, further studies are needed to confirm our findings.</p>","PeriodicalId":10847,"journal":{"name":"Crohn's & Colitis 360","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10923208/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Crohn's & Colitis 360","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/crocol/otae009","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Ulcerative colitis (UC) causes long-lasting inflammation and ulcers in the gut. Limited observational data are available linking dietary magnesium intake and UC. In the present study, we aimed to investigate the association between dietary magnesium intake and UC in adults.

Methods: The current population-based case-control study was performed on 109 UC patients and 218 age (±2 years) and sex-matched controls. The diagnosis of UC was made according to the standard criteria by a gastroenterology specialist. Dietary intakes were assessed using a validated self-administrated 106-item dish-based Food Frequency Questionnaire (FFQ). We also used a pretested questionnaire to collect data on potential confounders.

Results: Individuals in the top tertile of magnesium intake were less likely to have UC compared with those in the bottom tertile. A significant inverse relationship was found between dietary magnesium intake and UC (odds ratio [OR]: 0.32, 95% confidence interval [CI]: 0.18-0.59) in the crude model. This relationship was also observed when we took several potential confounding into account (OR: 0.30, 95% CI: 0.14-0.68).

Conclusions: Adherence to a magnesium-rich diet may have a role in preventing UC. However, further studies are needed to confirm our findings.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
膳食镁摄入量与溃疡性结肠炎成反比:病例对照研究
背景:溃疡性结肠炎(UC溃疡性结肠炎(UC)会导致肠道长期炎症和溃疡。有关膳食镁摄入量与溃疡性结肠炎之间关系的观察数据有限。在本研究中,我们旨在调查成年人膳食镁摄入量与 UC 之间的关系:本研究以人群为基础,对 109 名 UC 患者和 218 名年龄(±2 岁)和性别匹配的对照者进行了病例对照研究。UC的诊断由消化内科专家根据标准标准做出。膳食摄入量采用经过验证的自填式106项食物频率问卷(FFQ)进行评估。我们还使用了一份预先测试的问卷来收集潜在混杂因素的数据:结果:镁摄入量最高三分位数的人与最低三分位数的人相比,患 UC 的可能性较低。在粗略模型中发现,膳食镁摄入量与 UC 之间存在明显的反向关系(几率比 [OR]:0.32,95% 置信区间 [CI]:0.18-0.59)。当我们将几种潜在的混杂因素考虑在内时,也观察到了这种关系(OR:0.30,95% CI:0.14-0.68):结论:坚持富含镁的饮食可能对预防 UC 有一定作用。结论:坚持富含镁的饮食可能对预防 UC 有一定作用,但还需要进一步的研究来证实我们的发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Crohn's & Colitis 360
Crohn's & Colitis 360 Medicine-Gastroenterology
CiteScore
2.50
自引率
0.00%
发文量
41
审稿时长
12 weeks
期刊最新文献
Real-World Treatment Outcomes Associated With Early Versus Delayed Vedolizumab Initiation in Patients With Ulcerative Colitis. Like a Punch in the Gut: A Novel Perspective On Annual Recurrences of Ulcerative Colitis. Interventions for Adjunctive Care in Patients With Inflammatory Bowel Disease and Permanent Ileostomy: A Systematic Review. Clinical Approach to STRIDE-II in Real-Life Settings: Analysis and Practical Recommendations. Evaluation of the Symptoms and Clinical Characteristics of Crohn's Disease and Ulcerative Colitis That Affect Healthcare Providers' Treatment Choices.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1