Comparison of absolute renal uptake by using Tc-99m MAG-3 and Tc-99m DMSA.

IF 1.3 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Nuclear Medicine Communications Pub Date : 2024-06-01 Epub Date: 2024-03-11 DOI:10.1097/MNM.0000000000001831

Hasnain Dilawar, Salman Habib, Razia Rana, Akhtar Ahmed, Javaid Iqbal, Talal Abdul Rehman, Imran Hadi, Shazia Fatima

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Abstract

Purpose: The purpose of this study is to compare the value of absolute renal uptake (ARU %) in patients by using Tc-99m MAG-3 and Tc-99m DMSA scan.

Material and methods: Absolute renal uptake is calculated using Tc-99m MAG-3 and Tc-99m DMSA in renal scintigraphy, Itoh and Tauex kidney depth methods used, respectively. n = 40 adult patients of both genders were included. All patients underwent Tc-99m MAG-3 and Tc-99m DMSA, respectively.

Results: The values of ARU (%) were calculated separately in selected patients n = 40, (left = 17, right = 23 normal functioning kidneys) by MAG-3 and DMSA. Absolute renal uptake (%) of Tc-99m MAG-3 in left kidneys was found to be 15.2 ± 3.4, with spilt renal function 79.2 ± 14.7 and ARU (%) in right kidneys 16.2 ± 3.4 with spilt renal function 77.5 ± 19. Absolute renal uptake of Tc-99m DMSA in left kidneys was 17.5 ± 3.2 and in right kidneys 17.9 ± 4.5 with spilt renal function 81.8 ± 10.7 and 79.3 ± 13.8 for left and right kidney, respectively. Statistical analysis showed strong Pearson correlation.

Conclusion: Absolute renal uptake % was found to be more reliable in cases of bilateral compromised kidneys. ARU (%) calculated by Tc-99m MAG-3 solely can be used as predictor of renal function. The use of Tc-99m MAG-3 has more advantages than Tc-99m DMSA alone in renal scintigraphy as dynamic scintigraphy gives less radiation burden to patient, more information regarding renal function, and shorter stay time at hospital in comparison to static renal imaging. SRF % is less reliable than ARU (%).

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使用 Tc-99m MAG-3 和 Tc-99m DMSA 比较绝对肾摄取量。

目的：本研究的目的是比较使用 Tc-99m MAG-3 和 Tc-99m DMSA 扫描时患者肾脏绝对摄取率（ARU %）的数值：在肾脏闪烁扫描中使用 Tc-99m MAG-3 和 Tc-99m DMSA 计算肾脏绝对摄取量，分别使用 Itoh 和 Tauex 肾脏深度法。所有患者分别接受了 Tc-99m MAG-3 和 Tc-99m DMSA 检查：通过 MAG-3 和 DMSA 分别计算了选定患者 n = 40（左侧 = 17，右侧 = 23 个功能正常的肾脏）的 ARU 值（%）。发现左肾对 Tc-99m MAG-3 的绝对肾摄取量（%）为 15.2 ± 3.4（肾功能受损时为 79.2 ± 14.7），右肾对 Tc-99m MAG-3 的绝对肾摄取量（%）为 16.2 ± 3.4（肾功能受损时为 77.5 ± 19）。左肾对 Tc-99m DMSA 的绝对肾摄取量为（17.5 ± 3.2），右肾为（17.9 ± 4.5），左肾和右肾的肾功能分别为（81.8 ± 10.7）和（79.3 ± 13.8）。统计分析显示，两者之间存在很强的皮尔逊相关性：结论：在双肾受损的病例中，肾绝对摄取率更为可靠。仅用 Tc-99m MAG-3 计算出的 ARU（%）可作为肾功能的预测指标。在肾脏闪烁成像中使用 Tc-99m MAG-3 比单独使用 Tc-99m DMSA 更有优势，因为与静态肾脏成像相比，动态闪烁成像给患者带来的辐射负担更小，有关肾功能的信息更多，住院时间更短。SRF % 不如 ARU (%) 可靠。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nuclear Medicine Communications 医学-核医学

CiteScore

2.20

自引率

6.70%

发文量

212

审稿时长

3-8 weeks

期刊介绍： Nuclear Medicine Communications, the official journal of the British Nuclear Medicine Society, is a rapid communications journal covering nuclear medicine and molecular imaging with radionuclides, and the basic supporting sciences. As well as clinical research and commentary, manuscripts describing research on preclinical and basic sciences (radiochemistry, radiopharmacy, radiobiology, radiopharmacology, medical physics, computing and engineering, and technical and nursing professions involved in delivering nuclear medicine services) are welcomed, as the journal is intended to be of interest internationally to all members of the many medical and non-medical disciplines involved in nuclear medicine. In addition to papers reporting original studies, frankly written editorials and topical reviews are a regular feature of the journal.