A Review on the Use of Modern Computational Methods in Alzheimer's Disease-Detection and Prediction.

Arka De, Tusar Kanti Mishra, Sameeksha Saraf, Balakrushna Tripathy, Shiva Shankar Reddy
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Abstract

Discoveries in the field of medical sciences are blooming rapidly at the cost of voluminous efforts. Presently, multidisciplinary research activities have been especially contributing to catering cutting-edge solutions to critical problems in the domain of medical sciences. The modern age computing resources have proved to be a boon in this context. Effortless solutions have become a reality, and thus, the real beneficiary patients are able to enjoy improved lives. One of the most emerging problems in this context is Alzheimer's disease, an incurable neurological disorder. For this, early diagnosis is made possible with benchmark computing tools and schemes. These benchmark schemes are the results of novel research contributions being made intermittently in the timeline. In this review, an attempt is made to explore all such contributions in the past few decades. A systematic review is made by categorizing these contributions into three folds, namely, First, Second, and Third Generations. However, priority is given to the latest ones as a handful of literature reviews are already available for the classical ones. Key contributions are discussed vividly. The objectives set for this review are to bring forth the latest discoveries in computing methodologies, especially those dedicated to the diagnosis of Alzheimer's disease. A detailed timeline of the contributions is also made available. Performance plots for certain key contributions are also presented for better graphical understanding.

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现代计算方法在阿尔茨海默病检测和预测中的应用综述。
医学科学领域的发现正以巨大的努力迅速绽放。目前,多学科研究活动尤其有助于为医学科学领域的关键问题提供最先进的解决方案。在这方面,现代计算机资源已被证明是一个福音。毫不费力的解决方案已成为现实,因此,真正的受益者病人能够享受到更好的生活。阿尔茨海默病是这方面最新出现的问题之一,这是一种无法治愈的神经系统疾病。为此,基准计算工具和方案使早期诊断成为可能。这些基准方案是在时间轴上不时出现的新研究成果。在本综述中,我们试图探讨过去几十年中所有此类贡献。本综述将这些贡献分为三类,即第一代、第二代和第三代。不过,由于对经典贡献的文献综述屈指可数,因此我们优先考虑最新的贡献。对主要贡献进行了生动的讨论。本综述的目标是介绍计算方法的最新发现,尤其是那些专门用于阿尔茨海默病诊断的方法。此外,还提供了有关贡献的详细时间表。此外,还提供了某些重要贡献的性能图,以便读者更好地理解。
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