[Biochemical diagnosis of duodenitis].

E Siegmund, W Dummler, D Tessmann, K H Nagel, K Erdmann
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Abstract

The activities of enteropeptidase, alanine aminopeptidase, sucrase, and leucine aminopeptidase were determined in mucosa biopsies taken from three defined places of the duodenum and in duodenal juice. We examined 23 adults with a histological proven normal mucosa and 10 patients suffering from duodenitis grade I. Using multivariate evaluation of all the four enzyme activities of the three mucosa sites, we could differentiate duodenitis from normal mucosa with an efficiency of 88%.

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[十二指肠炎的生化诊断]。
肠肽酶、丙氨酸氨基肽酶、蔗糖酶和亮氨酸氨基肽酶的活性在十二指肠粘膜活检和十二指肠液中测定。我们检查了23名组织学证实的正常粘膜的成年人和10名i级十二指肠炎患者。通过对三个粘膜部位的所有四种酶活性的多变量评估,我们可以以88%的效率区分十二指肠炎和正常粘膜。
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