Use of sarolaner in the treatment of tungiasis in naturally infested dogs.

Brazilian journal of veterinary medicine Pub Date : 2024-03-13 eCollection Date: 2024-01-01 DOI:10.29374/2527-2179.bjvm000224
Rafaella Tortoriello, Natália Lôres Lopes, Bianca Bianco Paschoalino Linhares, Thais Ribeiro Correia, Julio Israel Fernandes
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Abstract

Tungiasis is an endemic dermatological parasitic zoonosis in Latin America, caused by the sand flea Tunga spp. (Siphonaptera, Tungidae), which promotes intense discomfort, swelling, erythema, itching, pain, secondary bacterial infection, cellulitis and necrosis. Sarolaner has been used to control different ectoparasites, but there is no record of its use for the treatment of tungiasis in dogs. The objective of this study was to evaluate the effectiveness of sarolaner for the treatment dogs naturally infested by Tunga spp. kept in the same infested environment. Three of four animals were medicated with sarolaner orally with a single dose of 2 mg/kg, as recommended by the manufacturer, and one animal remained without medication. After 24 hours, the fleas from all four dogs were mechanically removed. The animals were reevaluated on days +15 and +30 to assess possible reinfestation. The medicated animals remained free of fleas, while the untreated animal had fleas on the days previously defined for reevaluation. We can thus conclude that the use of sarolaner is an effective choice for tungiasis treatment.

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使用沙罗来纳治疗自然感染的狗的东革热。
恙虫病是拉丁美洲的一种地方性皮肤寄生虫病,由沙跳蚤 Tunga spp.(Siphonaptera,恙虫科)引起,会导致强烈不适、肿胀、红斑、瘙痒、疼痛、继发细菌感染、蜂窝组织炎和坏死。沙乐果曾被用于控制不同的体外寄生虫,但目前还没有使用沙乐果治疗犬桐子虫病的记录。本研究的目的是评估 Sarolaner 对治疗自然感染 Tunga spp.按照生产商的建议,四只动物中有三只口服了2毫克/千克单剂量的沙乐果,还有一只动物没有服药。24 小时后,四只狗身上的跳蚤均被机械清除。在第 +15 天和 +30 天再次对动物进行评估,以确定是否可能出现再次感染。使用药物的动物仍然没有跳蚤,而未使用药物的动物在重新评估的前几天仍有跳蚤。因此,我们可以得出结论,使用沙鲁胺酯可以有效治疗牛皮癣。
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