Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions.

Guy Hajj-Boutros, Andréa Faust, John Muscedere, Perry Kim, Naji Abumrad, Stéphanie Chevalier, Mylene Aubertin-Leheudre, Howard Bergman, Dawn Bowdish, Jessica Burford, Stacy Carrington-Lawrence, Hélène Côté, David E Dawe, Philipe de Souto Barreto, Colin Farrelly, Robert Fowler, Gilles Gouspillou, Lea Harrington, Sofie Lautrup, Susan Howlett, Mahdi Imani, James Kirkland, George Kuchel, Frédérick A Mallette, José A Morais, John C Newman, Daryl Pullman, Felipe Sierra, Jeremy Van Raamsdonk, Jennifer Watt, Rebecca Jane Rylett, Gustavo Duque
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Abstract

The inaugural Canadian Conferences on Translational Geroscience were held as 2 complementary sessions in October and November 2023. The conferences explored the profound interplay between the biology of aging, social determinants of health, the potential societal impact of geroscience, and the maintenance of health in aging individuals. Although topics such as cellular senescence, molecular and genetic determinants of aging, and prevention of chronic disease were addressed, the conferences went on to emphasize practical applications for enhancing older people's quality of life. This article summarizes the proceeding and underscores the synergy between clinical and fundamental studies. Future directions highlight national and global collaborations and the crucial integration of early-career investigators. This work charts a course for a national framework for continued innovation and advancement in translational geroscience in Canada.

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领航加拿大老年转化科学:对当前进展和未来方向的全面评估》。
首届加拿大老年转化科学会议于 2023 年 10 月和 11 月举行,是两个互补的会议。会议探讨了衰老生物学、健康的社会决定因素、老年科学的潜在社会影响以及衰老个体的健康维护之间的深刻相互作用。虽然会议讨论了细胞衰老、老龄化的分子和遗传决定因素以及慢性疾病预防等主题,但会议接着强调了提高老年人生活质量的实际应用。本手稿对会议进行了总结,并强调了临床和基础研究之间的协同作用。未来的发展方向突出了国家和全球合作以及早期研究人员的重要整合。这项工作为加拿大地质科学转化领域的持续创新和进步制定了国家框架。
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