Novel Strategies in Diagnosing Heart Failure with Preserved Ejection Fraction: A Comprehensive Literature Review.

IF 3.1 Q2 PERIPHERAL VASCULAR DISEASE High Blood Pressure & Cardiovascular Prevention Pub Date : 2024-03-01 Epub Date: 2024-03-15 DOI:10.1007/s40292-024-00629-1
Costantino Mancusi, Christian Basile, Carmen Spaccarotella, Giuseppe Gargiulo, Ilaria Fucile, Stefania Paolillo, Paola Gargiulo, Ciro Santoro, Lina Manzi, Federica Marzano, Pasquale Ambrosino, Nicola De Luca, Giovanni Esposito
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Abstract

Heart failure (HF) with preserved ejection fraction (HFpEF) is a prevalent global condition affecting approximately 50% of the HF population. With the aging of the worldwide population, its incidence and prevalence are expected to rise even further. Unfortunately, until recently, no effective medications were available to reduce the high mortality and hospitalization rates associated with HFpEF, making it a significant unmet need in cardiovascular medicine. Although HFpEF is commonly defined as HF with normal ejection fraction and elevated left ventricular filling pressure, performing invasive hemodynamic assessments on every individual suspected of having HFpEF is neither feasible nor practical. Consequently, several clinical criteria and diagnostic tools have been proposed to aid in diagnosing HFpEF. Overall, these criteria and tools are designed to assist healthcare professionals in identifying and evaluating patients who may have HFpEF based on a combination of signs, symptoms, biomarkers, and non-invasive imaging findings. By employing these non-invasive diagnostic approaches, clinicians can make informed decisions regarding the best pharmacological and rehabilitation strategies for individuals with suspected HFpEF. This literature review aims to provide an overview of all currently available methods for diagnosing and monitoring this disabling condition.

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诊断射血分数保留型心力衰竭的新策略:全面文献综述
射血分数保留型心力衰竭(HF)是一种全球流行的疾病,约占心力衰竭患者的 50%。随着全球人口的老龄化,预计其发病率和流行率还会进一步上升。遗憾的是,直到最近,还没有有效的药物能降低与高房颤相关的高死亡率和住院率,这使其成为心血管医学中一个尚未满足的重大需求。虽然 HFpEF 通常被定义为射血分数正常但左心室充盈压升高的 HF,但对每一个疑似 HFpEF 患者进行有创血液动力学评估既不可行也不实际。因此,人们提出了一些临床标准和诊断工具来帮助诊断 HFpEF。总体而言,这些标准和工具旨在帮助医护人员根据体征、症状、生物标志物和非侵入性成像结果,识别和评估可能患有 HFpEF 的患者。通过采用这些非侵入性诊断方法,临床医生可以为疑似 HFpEF 患者做出关于最佳药物治疗和康复策略的明智决定。本文献综述旨在概述目前可用于诊断和监测这种致残性疾病的所有方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.70
自引率
3.30%
发文量
57
期刊介绍: High Blood Pressure & Cardiovascular Prevention promotes knowledge, update and discussion in the field of hypertension and cardiovascular disease prevention, by providing a regular programme of independent review articles covering key aspects of the management of hypertension and cardiovascular diseases. The journal includes:   Invited ''State of the Art'' reviews.  Expert commentaries on guidelines, major trials, technical advances.Presentation of new intervention trials design.''Pros and Cons'' or round tables on controversial issues.Statements on guidelines from hypertension and cardiovascular scientific societies.Socio-economic issues.Cost/benefit in prevention of cardiovascular diseases.Monitoring of healthcare systems.News and views from the Italian Society of Hypertension (including abstracts).All manuscripts are subject to peer review by international experts. Letters to the editor are welcomed and will be considered for publication.
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