Performance-enhancing substances in sport: A scientometric review of 75 years of research.

IF 2.6 3区 医学 Q2 BIOCHEMICAL RESEARCH METHODS Drug Testing and Analysis Pub Date : 2025-01-01 Epub Date: 2024-03-16 DOI:10.1002/dta.3677
Alessandro Carollo, Ornella Corazza, Maria Mantovani, Nicolò Silvestrini, Olivier Rabin, Gianluca Esposito
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Abstract

The use of performance-enhancing substances not only undermines the core values of sports but also poses significant health risks to athletes. In a fast-evolving doping environment, where sport professionals are constantly seeking novel and illegal means to bypass doping tests, and new substances are regularly detected on the drug market, it is crucial to inform authorities with updated evidence emerging from scientific research. The current study aims to (i) outline the structure of knowledge in the literature on performance enhancers in sports (i.e., most active countries, main sources, most productive authors, and most frequently used keywords); (ii) identify the most impactful documents in the field; and (iii) uncover the main domains of research in the literature. To do so, we conducted a comprehensive scientometric analysis of the literature on doping, sourcing our data from Scopus. Our research involved a document co-citation analysis of 193,076 references, leading to the identification of the 51 most influential documents and seven key thematic areas within the doping literature. Our results indicate that the scientific community has extensively studied the most prevalent doping classes, such as anabolic agents and peptide hormones, and little is still known about the use of contaminated supplements or other types of enhancers identified as emergent trends. Concurrently, technological advancements contributed to the development of more sophisticated doping detection techniques, using blood or urine samples. More recently, the focus has shifted towards the athlete biological passport, with research efforts aimed at identifying biomarkers indicative of doping. The dynamic nature of doping methods underlines the necessity for more robust educational campaigns, aiming at raising awareness among sports professionals and their entourage about the dangers of doping and the intricacies of its control mechanisms.

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体育运动中的提高成绩物质:对 75 年研究的科学计量学回顾。
使用提高成绩的物质不仅有损于体育运动的核心价值,而且对运动员的健康构成重大威胁。在快速发展的兴奋剂环境中,体育专业人员不断寻求新的非法手段来绕过兴奋剂检测,药物市场上也经常检测出新的物质,因此,向有关当局提供最新的科学研究证据至关重要。本研究旨在:(i) 概述有关体育运动中成绩增强剂的文献的知识结构(即最活跃的国家、主要来源、最有成果的作者和最常用的关键词);(ii) 确定该领域最具影响力的文献;(iii) 挖掘文献中的主要研究领域。为此,我们对有关兴奋剂的文献进行了全面的科学计量分析,数据来源于 Scopus。我们的研究包括对 193,076 篇参考文献进行文献共引分析,最终确定了兴奋剂文献中最具影响力的 51 篇文献和七个关键主题领域。我们的研究结果表明,科学界已对同化制剂和肽类激素等最普遍的兴奋剂类别进行了广泛研究,而对于被确定为新兴趋势的受污染补充剂或其他类型的增强剂的使用情况仍知之甚少。与此同时,技术的进步促进了利用血液或尿液样本进行兴奋剂检测技术的发展。最近,研究重点已转向运动员的生物护照,研究工作旨在确定表明使用兴奋剂的生物标志物。使用兴奋剂方法的动态性质突出表明,有必要开展更加有力的教育活动,以提高体育 专业人员及其随行人员对使用兴奋剂的危害及其控制机制的复杂性的认识。
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来源期刊
Drug Testing and Analysis
Drug Testing and Analysis BIOCHEMICAL RESEARCH METHODS-CHEMISTRY, ANALYTICAL
CiteScore
5.90
自引率
24.10%
发文量
191
审稿时长
2.3 months
期刊介绍: As the incidence of drugs escalates in 21st century living, their detection and analysis have become increasingly important. Sport, the workplace, crime investigation, homeland security, the pharmaceutical industry and the environment are just some of the high profile arenas in which analytical testing has provided an important investigative tool for uncovering the presence of extraneous substances. In addition to the usual publishing fare of primary research articles, case reports and letters, Drug Testing and Analysis offers a unique combination of; ‘How to’ material such as ‘Tutorials’ and ‘Reviews’, Speculative pieces (‘Commentaries’ and ‘Perspectives'', providing a broader scientific and social context to the aspects of analytical testing), ‘Annual banned substance reviews’ (delivering a critical evaluation of the methods used in the characterization of established and newly outlawed compounds). Rather than focus on the application of a single technique, Drug Testing and Analysis employs a unique multidisciplinary approach to the field of controversial compound determination. Papers discussing chromatography, mass spectrometry, immunological approaches, 1D/2D gel electrophoresis, to name just a few select methods, are welcomed where their application is related to any of the six key topics listed below.
期刊最新文献
Gene Doping Detection From the Perspective of 3D Genome. The Impact of Triptorelin on Hormone Levels in Human and Its Metabolite Confirmation Using Liquid Chromatography-Ion Trap/Time-of-Flight Mass Spectrometry (LC/MS-IT-TOF) and Liquid Chromatography-Orbitrap (LC-Orbitrap) for Doping Control Analysis. Infant exposure to drugs of abuse investigated by hair analysis. Performance-enhancing substances in sport: A scientometric review of 75 years of research. Single hair analysis for gamma-hydroxybutyric acid-Method optimization, validation, and application.
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