Making genome editing a success story in Africa

IF 33.1 1区 生物学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Nature biotechnology Pub Date : 2024-03-19 DOI:10.1038/s41587-024-02187-2
Hussein M. Abkallo, Patrick Arbuthnot, Thomas O. Auer, Dave K. Berger, Johan Burger, Ereck Chakauya, Jean-Paul Concordet, Abdoulaye Diabate, Vincenzo Di Donato, Jan-Hendrik Groenewald, Amadou Guindo, Lizette L. Koekemoer, Florence Nazare, Tony Nolan, Fredros Okumu, Emma Orefuwa, Lily Paemka, Lucia Prieto-Godino, Steven Runo, Marie Sadler, Kassahun Tesfaye, Leena Tripathi, Charles Wondji
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让基因组编辑成为非洲的成功故事
与其他生物技术类似,基因组编辑技术在非洲也面临巨大障碍。这些障碍包括监管的不确定性、获得实验室、设备和分子生物学试剂的途径有限、训练有素的专业人员短缺以及海外移民回国率低。投资也很少:大多数国家用于研发的资金不到国内生产总值(GDP)的 1%。非洲机构对外部资金的依赖、与全球北方国家的不平等合作以及外国实体对知识产权和许可的控制进一步阻碍了进步。此外,将生物技术纳入中小学和大学课程的程度较低,对风险的认识不准确,公众支持度明显较低(往往是由于错误信息造成的),因此政治意愿不足。在资源有限的环境中,减少基因组编辑提供的基于遗传学的创新障碍,可使当地创新者在对非洲生物技术经济发展至关重要的领域取得更大成功。此外,基于基因组编辑的健康产品(包括新型基因疗法)可对公共健康产生显著影响。
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来源期刊
Nature biotechnology
Nature biotechnology 工程技术-生物工程与应用微生物
CiteScore
63.00
自引率
1.70%
发文量
382
审稿时长
3 months
期刊介绍: Nature Biotechnology is a monthly journal that focuses on the science and business of biotechnology. It covers a wide range of topics including technology/methodology advancements in the biological, biomedical, agricultural, and environmental sciences. The journal also explores the commercial, political, ethical, legal, and societal aspects of this research. The journal serves researchers by providing peer-reviewed research papers in the field of biotechnology. It also serves the business community by delivering news about research developments. This approach ensures that both the scientific and business communities are well-informed and able to stay up-to-date on the latest advancements and opportunities in the field. Some key areas of interest in which the journal actively seeks research papers include molecular engineering of nucleic acids and proteins, molecular therapy, large-scale biology, computational biology, regenerative medicine, imaging technology, analytical biotechnology, applied immunology, food and agricultural biotechnology, and environmental biotechnology. In summary, Nature Biotechnology is a comprehensive journal that covers both the scientific and business aspects of biotechnology. It strives to provide researchers with valuable research papers and news while also delivering important scientific advancements to the business community.
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