Breaking ground: ABLs and TMKs as co-receptors to perceive extracellular auxin

Guan-Zhu Wang , Xue Wu , Ge-Fei Hao
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Abstract

Auxin is an important phytohormone that regulates a string of vital rapid responses, and its signaling perception mechanism has been one of the hot spots of research. It has been shown that the ABP1/TMKs module is involved in regulating extracellular auxin signaling, however, the role of ABP1 as an auxin receptor is highly controversial. Therefore, the mechanism of quintessential TMKs sense extracellular auxin remains unresolved. Recently, a study identified two new auxin-binding proteins, ABL1 and ABL2, which directly interact with TMKs to perceive apoplast auxin. This groundbreaking research unravels the mystery surrounding how plants perceive extracellular auxin signals.

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突破性进展:ABL 和 TMK 作为共同受体感知细胞外的植物生长素
叶绿素是一种重要的植物激素,可调控一系列重要的快速反应,其信号传导机制一直是研究的热点之一。已有研究表明,ABP1/TMKs 模块参与调控细胞外的叶绿素信号转导,但 ABP1 作为叶绿素受体的作用却存在很大争议。因此,五元 TMKs 感受细胞外植物生长素的机制仍悬而未决。最近,一项研究发现了两个新的植物生长素结合蛋白 ABL1 和 ABL2,它们直接与 TMKs 相互作用以感知细胞外植物生长素。这项突破性研究揭开了植物如何感知细胞外植物生长素信号的神秘面纱。
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