A. K. Chigasova, L. A. Ostrovskaya, D. B. Korman, N. V. Bluhterova
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引用次数: 0
Abstract
A comparative study of the cytotoxic activity and mechanism of action of polyacrylates containing gold (aurumacryl) and silver (argacryl) against human tumor cells (MCF-7 cell culture) has been carried out. The high cytotoxic activity of the drugs has been shown. Argacryl was found to be 20 times more effective than aurumacryl. It was found that apoptosis was the dominant mechanism in the death of tumor cells induced by aurumacryl and argacryl. Differences in the effect of drugs on the DNA structure of tumor cells were revealed.
BiophysicsBiochemistry, Genetics and Molecular Biology-Biophysics
CiteScore
1.20
自引率
0.00%
发文量
67
期刊介绍：
Biophysics is a multidisciplinary international peer reviewed journal that covers a wide scope of problems related to the main physical mechanisms of processes taking place at different organization levels in biosystems. It includes structure and dynamics of macromolecules, cells and tissues; the influence of environment; energy transformation and transfer; thermodynamics; biological motility; population dynamics and cell differentiation modeling; biomechanics and tissue rheology; nonlinear phenomena, mathematical and cybernetics modeling of complex systems; and computational biology. The journal publishes short communications devoted and review articles.
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