Exploring the Therapeutic Potential of Peritoneal Dialysis (PD) in the Treatment of Neurological Disorders.

IF 3.2 4区医学 Q3 CELL & TISSUE ENGINEERING Cell Transplantation Pub Date : 2024-01-01 DOI:10.1177/09636897241236576

Muyuan Cheng, Yuchuan Ding, Enoch Kim, Xiaokun Geng

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Abstract

Peritoneal dialysis (PD) is a well-established renal replacement therapy commonly employed in clinical practice. While its primary application is in the treatment of kidney disease, its potential in addressing other systemic disorders, including neurological diseases, has garnered increasing interest. This study provides a comprehensive overview of the related technologies, unique advantages, and clinical applications of PD in the context of neurological disorders. By exploring the mechanism underlying PD, its application in neurological diseases, and associated complications, we addressed the feasibility and benefits of PD as an adjunct therapy for various neurological conditions. Our study aims to highlight its role in detoxification and symptom management, as well as its advantages over other universally accepted methods of renal replacement therapy. Our goal is to bring to the spotlight the therapeutic potential of PD in neurological diseases, such as stroke, stimulate further research, and broaden the scope of its application in the clinical setting.

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探索腹膜透析 (PD) 治疗神经系统疾病的潜力。

腹膜透析（PD）是临床上常用的一种成熟的肾脏替代疗法。虽然腹膜透析的主要应用是治疗肾脏疾病，但它在治疗包括神经系统疾病在内的其他系统疾病方面的潜力也引起了越来越多的关注。本研究全面概述了 PD 在神经系统疾病方面的相关技术、独特优势和临床应用。通过探索 PD 的内在机制、在神经系统疾病中的应用以及相关并发症，我们探讨了 PD 作为各种神经系统疾病辅助疗法的可行性和益处。我们的研究旨在强调其在解毒和症状控制方面的作用，以及与其他普遍接受的肾脏替代疗法相比的优势。我们的目标是让人们关注 PD 在神经系统疾病（如中风）中的治疗潜力，促进进一步的研究，并扩大其在临床环境中的应用范围。

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来源期刊

Cell Transplantation 生物-细胞与组织工程

CiteScore

6.00

自引率

3.00%

发文量

审稿时长

6 months

期刊介绍： Cell Transplantation, The Regenerative Medicine Journal is an open access, peer reviewed journal that is published 12 times annually. Cell Transplantation is a multi-disciplinary forum for publication of articles on cell transplantation and its applications to human diseases. Articles focus on a myriad of topics including the physiological, medical, pre-clinical, tissue engineering, stem cell, and device-oriented aspects of the nervous, endocrine, cardiovascular, and endothelial systems, as well as genetically engineered cells. Cell Transplantation also reports on relevant technological advances, clinical studies, and regulatory considerations related to the implantation of cells into the body in order to provide complete coverage of the field.