Abdominal normothermic regional perfusion in the United States: current state and future directions.

IF 1.8 4区 医学 Q3 TRANSPLANTATION Current Opinion in Organ Transplantation Pub Date : 2024-06-01 Epub Date: 2024-03-20 DOI:10.1097/MOT.0000000000001144
Anji Wall, Amar Gupta, Giuliano Testa
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Abstract

Purpose of review: Normothermic regional perfusion (NRP) is a novel procurement technique for donation after circulatory death (DCD) in the United States. It was pioneered by cardiothoracic surgery programs and is now being applied to abdominal-only organ donors by abdominal transplant programs.

Recent findings: Liver and kidney transplantation from thoracoabdominal NRP (TA-NRP) donors in the United States was found to have lower rates of delayed kidney graft function and similar graft and patient survival versus recipients of cardiac super rapid recovery (SRR) DCD donors. The excellent outcomes with NRP have prompted the expansion of NRP technology to abdominal transplant programs.

Summary: Excellent early outcomes with liver and kidney transplantation have prompted the growth of NC-NRP procurement for abdominal-only DCD donors across the US, and now requires standardization of technical and nontechnical aspects of this procedure.

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美国的腹部常温区域灌注:现状与未来方向。
审查目的:在美国,常温区域灌注(NRP)是一种用于循环死亡(DCD)后捐献的新型采购技术。该技术由心胸外科项目首创,目前腹腔移植项目正将其应用于腹腔器官捐献者:最近的研究结果:在美国,与心脏超快速恢复(SRR)DCD 供体的受体相比,胸腹腔 NRP(TA-NRP)供体的肝脏和肾脏移植的肾脏移植功能延迟率较低,移植器官和患者存活率相似。摘要:肝脏和肾脏移植的早期疗效极佳,促使全美越来越多地为腹腔DCD供体进行NC-NRP采购,现在需要对这一手术的技术和非技术方面进行标准化。
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来源期刊
CiteScore
4.10
自引率
4.50%
发文量
124
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Current Opinion in Organ Transplantation is an indispensable resource featuring key, up-to-date and important advances in the field from around the world. Led by renowned guest editors for each section, every bimonthly issue of Current Opinion in Organ Transplantation delivers a fresh insight into topics such as stem cell transplantation, immunosuppression, tolerance induction and organ preservation and procurement. With 18 sections in total, the journal provides a convenient and thorough review of the field and will be of interest to researchers, surgeons and other healthcare professionals alike.
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