Progress in the relationship between mechanical ventilation parameters and ventilator-related complications during perioperative anesthesia.

IF 3.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Postgraduate Medical Journal Pub Date : 2024-08-16 DOI:10.1093/postmj/qgae035
Hu Yue, Tao Yong
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Abstract

Background: Mechanical ventilation, as an important respiratory support, plays an important role in general anesthesia and it is the cornerstone of intraoperative management of surgical patients. Different from spontaneous respiration, intraoperative mechanical ventilation can lead to postoperative lung injury, and its impact on surgical mortality cannot be ignored. Postoperative lung injury increases hospital stay and is related to preoperative conditions, anesthesia time, and intraoperative ventilation settings.

Method: Through reading literature and research reports, the relationship between perioperative input parameters and output parameters related to mechanical ventilation and ventilator-related complications was reviewed, providing reference for the subsequent setting of input parameters of mechanical ventilation and new ventilation strategies.

Results: The parameters of inspiratory pressure rise time and inspiratory time can change the gas distribution, gas flow rate and airway pressure into the lungs, but there are few clinical studies on them. It can be used as a prospective intervention to study the effect of specific protective ventilation strategies on pulmonary complications after perioperative anesthesia.

Conclusion: There are many factors affecting lung function after perioperative mechanical ventilation. Due to the difference of human body, the ventilation parameters suitable for each patient are different, and the deviation of each ventilation parameter can lead to postoperative pulmonary complications. Inspiratory pressure rise time and inspiratory time will be used as the new ventilation strategy.

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围术期麻醉期间机械通气参数与呼吸机相关并发症之间关系的研究进展。
背景:机械通气作为一种重要的呼吸支持,在全身麻醉中发挥着重要作用,是手术患者术中管理的基石。与自主呼吸不同,术中机械通气可导致术后肺损伤,其对手术死亡率的影响不容忽视。术后肺损伤会延长住院时间,与术前情况、麻醉时间、术中通气设置等因素有关:方法:通过阅读文献和研究报告,回顾围手术期机械通气相关输入参数和输出参数与呼吸机相关并发症的关系,为后续机械通气输入参数的设置和新的通气策略提供参考:吸气压力上升时间和吸气时间参数可改变进入肺部的气体分布、气体流速和气道压力,但相关临床研究较少。可将其作为一种前瞻性干预手段,研究特定保护性通气策略对围手术期麻醉后肺部并发症的影响:结论:围术期机械通气后影响肺功能的因素很多。结论:影响围术期机械通气后肺功能的因素很多,由于人体的差异,适合每位患者的通气参数也不同,各通气参数的偏差可导致术后肺部并发症的发生。吸气压力上升时间和吸气时间将作为新的通气策略。
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来源期刊
Postgraduate Medical Journal
Postgraduate Medical Journal 医学-医学:内科
CiteScore
8.50
自引率
2.00%
发文量
131
审稿时长
2.5 months
期刊介绍: Postgraduate Medical Journal is a peer reviewed journal published on behalf of the Fellowship of Postgraduate Medicine. The journal aims to support junior doctors and their teachers and contribute to the continuing professional development of all doctors by publishing papers on a wide range of topics relevant to the practicing clinician and teacher. Papers published in PMJ include those that focus on core competencies; that describe current practice and new developments in all branches of medicine; that describe relevance and impact of translational research on clinical practice; that provide background relevant to examinations; and papers on medical education and medical education research. PMJ supports CPD by providing the opportunity for doctors to publish many types of articles including original clinical research; reviews; quality improvement reports; editorials, and correspondence on clinical matters.
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