{"title":"VIDEOFLUOROSCOPIC EVALUATION OF THE IMPACT OF CAPSULE SIZE AND SUBJECT'S AGE AND GENDER ON CAPSULE SWALLOWING.","authors":"Laís Flavia de Souza Gutierres, Marina Rodrigues Montaldi, Weslania Viviane Nascimento, Roberto Oliveira Dantas","doi":"10.1590/S0004-2803.246102023-92","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>People recurrently have difficulties swallowing solid medications, which can be associated with the size of the medication and the age and gender of individuals.</p><p><strong>Objective: </strong>To evaluate the impact of capsule size and adults' age and gender on oral and pharyngeal capsule transit during capsule swallows.</p><p><strong>Methods: </strong>Videofluoroscopy was used to measure capsule oral and pharyngeal transit during swallows in 49 healthy individuals (17 men and 32 women), with a mean age of 46 years (ranging from 23 to 88 years). Smaller capsules were filled with 0.50 mL of barium sulfate, and larger capsules were filled with 0.95 mL of barium sulfate; the volume of liquid ingested with the capsules was also quantified in each ingestion. The measurements included the oral preparation time, oral transit time, swallowing reaction time, time to laryngeal vestibule closure, laryngeal vestibule closure duration, pharyngeal transit time, and upper esophageal sphincter opening duration.</p><p><strong>Results: </strong>The capsule size did not influence either the oral or pharyngeal transit time. Increased liquid volume was ingested with larger capsules and by people older than 40 years. The oral transit time was shorter in older adults (60-88 years), and the time to laryngeal vestibule closure was longer in women.</p><p><strong>Conclusion: </strong>The size of large capsules did not make a difference in oral or pharyngeal transit when compared with smaller capsules. The capsule size and the participant's age influenced the volume of liquid ingested - larger capsules and older individuals required a larger volume. The capsule oral transit was faster in individuals older than 60 years.</p><p><strong>Background: </strong>•Swallowing is influenced by the characteristics of what is being swallowed.</p><p><strong>Background: </strong>•There was no difference in swallowing capsules containing 0.50 mL or 0.95 mL.</p><p><strong>Background: </strong>•Larger capsules need more liquid ingestion to make swallowing easier.</p><p><strong>Background: </strong>•Individuals older than 40 years need a greater volume of liquid to swallow capsules than younger adults.</p>","PeriodicalId":35671,"journal":{"name":"Arquivos de Gastroenterologia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arquivos de Gastroenterologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/S0004-2803.246102023-92","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Background: People recurrently have difficulties swallowing solid medications, which can be associated with the size of the medication and the age and gender of individuals.
Objective: To evaluate the impact of capsule size and adults' age and gender on oral and pharyngeal capsule transit during capsule swallows.
Methods: Videofluoroscopy was used to measure capsule oral and pharyngeal transit during swallows in 49 healthy individuals (17 men and 32 women), with a mean age of 46 years (ranging from 23 to 88 years). Smaller capsules were filled with 0.50 mL of barium sulfate, and larger capsules were filled with 0.95 mL of barium sulfate; the volume of liquid ingested with the capsules was also quantified in each ingestion. The measurements included the oral preparation time, oral transit time, swallowing reaction time, time to laryngeal vestibule closure, laryngeal vestibule closure duration, pharyngeal transit time, and upper esophageal sphincter opening duration.
Results: The capsule size did not influence either the oral or pharyngeal transit time. Increased liquid volume was ingested with larger capsules and by people older than 40 years. The oral transit time was shorter in older adults (60-88 years), and the time to laryngeal vestibule closure was longer in women.
Conclusion: The size of large capsules did not make a difference in oral or pharyngeal transit when compared with smaller capsules. The capsule size and the participant's age influenced the volume of liquid ingested - larger capsules and older individuals required a larger volume. The capsule oral transit was faster in individuals older than 60 years.
Background: •Swallowing is influenced by the characteristics of what is being swallowed.
Background: •There was no difference in swallowing capsules containing 0.50 mL or 0.95 mL.
Background: •Larger capsules need more liquid ingestion to make swallowing easier.
Background: •Individuals older than 40 years need a greater volume of liquid to swallow capsules than younger adults.
期刊介绍：
The journal Arquivos de Gastroenterologia (Archives of Gastroenterology), a quarterly journal, is the Official Publication of the Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia IBEPEGE (Brazilian Institute for Studies and Research in Gastroenterology), Colégio Brasileiro de Cirurgia Digestiva - CBCD (Brazilian College of Digestive Surgery) and of the Sociedade Brasileira de Motilidade Digestiva - SBMD (Brazilian Digestive Motility Society). It is dedicated to the publishing of scientific papers by national and foreign researchers who are in agreement with the aim of the journal as well as with its editorial policies.
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