Emergencia hipertensiva como debut de síndrome de Cushing paraneoplásico

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-01 DOI:10.1016/j.hipert.2023.10.003

E. Rubio González, M. de Valdenebro Recio, M.I. Galán Fernández

引用次数: 0

Abstract

We present the case of a patient with a history of renal-vascular hypertension treated with stent one year previously, who attended the emergency room due to hypertensive emergency and dyspnea. Once the first suspicion of renal artery restenosis was ruled out with CT angiography, the study was completed, confirming the diagnosis of lung cancer through imaging and pathological anatomy. In the hormonal study, elevation of ACTH, hypercortisolism and analytical data of hyperaldosteronism were detected. With the final diagnosis of Cushing's syndrome secondary to ectopic production of ACTH, medical treatment was started, without being able to receive anything else due to the death of the patient after a few days.

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[高血压急症是副肿瘤性库欣综合征的首发症状]。

我们介绍的病例是一名一年前曾接受支架治疗的肾血管性高血压患者，因高血压急症和呼吸困难到急诊就诊。在通过 CT 血管造影排除肾动脉再狭窄的初步怀疑后，研究完成，通过影像学和病理解剖确诊为肺癌。在激素检查中，发现了促肾上腺皮质激素升高、皮质醇增多和高醛固酮血症的分析数据。最终诊断为继发于促肾上腺皮质激素异位分泌的库欣综合征，于是开始进行药物治疗，但由于几天后患者死亡，无法接受其他治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.