Meningococcal meningitis in Spain in the Horizon 2030: A position paper.

F Moraga-Llop, E Andradas, L C Blesa-Baviera, R Cantón, J González Del Castillo, F Martinón-Torres, E Moya, A Trilla, J Vazquez, R J Villena, J Ruiz-Galiana, P De Lucas Ramos, A García-Botella, A García-Lledó, T Hernández-Sampelayo, J Gómez-Pavón, M C Martín-Delgado, F J Martín Sánchez, M Martínez-Sellés, J M Molero García, S Moreno Guillén, F J Rodríguez-Artalejo, E Bouza
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Abstract

Meningococcal meningitis (MM) and invasive meningococcal disease remain a major public health problem that generates enormous public alarm. It is caused by Neisseria meningitidis, a Gram-negative diplococcus with an enormous capacity for acute and rapidly progressive disease, both episodic and epidemic in nature, with early diagnosis and treatment playing a major role. It occurs at any age, but is most common in children under 5 years of age followed by adolescents. Although most cases occur in healthy people, the incidence is higher in certain risk groups. Despite advances in reducing the incidence, it is estimated that in 2017 there were around 5 million new cases of MM worldwide, causing approximately 290,000 deaths and a cumulative loss of about 20,000,000 years of healthy life. In Spain, in the 2021/22 season, 108 microbiologically confirmed cases of MM were reported, corresponding to an incidence rate of 0.23 cases per 100,000 inhabitants. This is a curable and, above all, vaccine-preventable disease, for which the World Health Organisation has drawn up a roadmap with the aim of reducing mortality and sequelae by 2030. For all these reasons, the Illustrious Official College of Physicians of Madrid (ICOMEM) and the Medical Associations of 8 other provinces of Spain, have prepared this opinion document on the situation of MM in Spain and the resources and preparation for the fight against it in our country. The COVID-19 and Emerging Pathogens Committee of ICOMEM has invited experts in the field to participate in the elaboration of this document.

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2030 年地平线上的西班牙脑膜炎球菌:立场文件。
脑膜炎球菌性脑膜炎(MM)和侵袭性脑膜炎球菌病仍然是一个重大的公共卫生问题,引起了公众的极大恐慌。它是由奈瑟氏脑膜炎球菌引起的,奈瑟氏脑膜炎球菌是一种革兰氏阴性双球菌,具有急性和快速进展性疾病的巨大能力,既可偶发,也可流行,早期诊断和治疗起着重要作用。该病可发生于任何年龄,但最常见于 5 岁以下儿童,其次是青少年。虽然大多数病例发生在健康人身上,但某些高危人群的发病率更高。尽管在降低发病率方面取得了进展,但据估计,2017 年全球约有 500 万个 MM 新发病例,造成约 29 万人死亡,累计损失约 2000 万年的健康寿命。在西班牙,2021/22 年度共报告 108 例经微生物确诊的 MM 病例,发病率为每 10 万居民 0.23 例。这是一种可以治愈的疾病,尤其是可以通过疫苗预防的疾病,世界卫生组织已经为此制定了路线图,目标是在 2030 年之前降低死亡率和后遗症。鉴于上述原因,马德里杰出的官方医师学院(ICOMEM)和西班牙其他 8 个省的医学协会编写了这份意见书,介绍了西班牙的麻风病情况以及我国防治麻风病的资源和准备情况。ICOMEM 的 COVID-19 和新发病原体委员会邀请了该领域的专家参与本文件的编写。
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