Evaluation of preoperative coagulation function changes and deep vein thrombosis incidence in elderly patients with hip fractures.

Li-Tao Shi, Fan-Qiang Kong
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Abstract

Objective: This study involved an analysis of preoperative deep vein thrombosis (DVT) incidence and changes in coagulation function among elderly patients suffering from hip fractures. The objective was to offer guidance on the prevention and management of preoperative DVT in the lower extremities of elderly individuals with hip fractures.

Methods: A total of 282 elderly individuals with a hip fracture were enrolled and divided into two groups based on the location of the fracture: femoral intertrochanteric fracture (FIF, 161 individuals) and femoral neck fracture (FNF, 121 individuals). The two groups were compared with respect to baseline characteristics, including gender, age, and comorbid chronic diseases. Furthermore, the analysis encompassed the incidence of preoperative DVT in both lower extremities, along with seven coagulation parameters and platelet count before the surgical procedure.

Results: There was no significant difference in baseline information between the two groups. The incidence of preoperative DVT in the FIF group was higher than that in the FNF group, along with a significantly higher percentage of patients exhibiting increased levels of D-dimer and fibrinogen/fibrin degradation products (FDPs).

Conclusion: Preoperative hypercoagulability and a greater prevalence of DVT were observed in elderly individuals with FIF compared to individuals with FNF. This indicates that clinicians should pay attention to elderly patients with FIFs, especially those with increased D-dimer and FDP levels.

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评估老年髋部骨折患者术前凝血功能变化和深静脉血栓形成的发生率。
研究目的本研究分析了髋部骨折老年患者术前深静脉血栓(DVT)的发生率和凝血功能的变化。目的是为髋部骨折老年患者术前下肢深静脉血栓的预防和管理提供指导:方法:共招募了 282 名髋部骨折的老年患者,并根据骨折部位分为两组:股骨转子间骨折组(FIF,161 人)和股骨颈骨折组(FNF,121 人)。两组患者的基线特征进行了比较,包括性别、年龄和合并慢性疾病。此外,分析还包括术前双下肢深静脉血栓的发生率,以及手术前的七项凝血参数和血小板计数:结果:两组患者的基线资料无明显差异。FIF组术前深静脉血栓的发生率高于FNF组,D-二聚体和纤维蛋白原/纤维蛋白降解产物(FDPs)水平升高的患者比例也明显高于FNF组:结论:与 FNF 患者相比,FIF 老年患者术前出现高凝状态,且深静脉血栓的发生率更高。这表明临床医生应关注患有 FIF 的老年患者,尤其是那些 D-二聚体和 FDP 水平升高的患者。
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