A. I. Mikhalskii, J. A. Novoseltseva, A. A. Anashkina, A. N. Nekrasov
{"title":"Probabilistic Assessment of a Pentapeptide Composition Influence on Its Stability","authors":"A. I. Mikhalskii, J. A. Novoseltseva, A. A. Anashkina, A. N. Nekrasov","doi":"10.1134/s0005117923120032","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The influence of the arrangement of amino acid residues in a pentapeptide on its stability is being studied. A forecast of pentapeptide stability is made using the gradient boosting method, which allows one to evaluate the influence of each feature on the stability of the pentapeptide. Combinations of amino acid arrangements in the pentapeptide have been identified that make a significant contribution to its stability. It has been shown that the use of such combinations reduces the amount of data required to obtain a reliable prediction of pentapeptide stability.</p>","PeriodicalId":55411,"journal":{"name":"Automation and Remote Control","volume":null,"pages":null},"PeriodicalIF":0.6000,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Automation and Remote Control","FirstCategoryId":"94","ListUrlMain":"https://doi.org/10.1134/s0005117923120032","RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"AUTOMATION & CONTROL SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
The influence of the arrangement of amino acid residues in a pentapeptide on its stability is being studied. A forecast of pentapeptide stability is made using the gradient boosting method, which allows one to evaluate the influence of each feature on the stability of the pentapeptide. Combinations of amino acid arrangements in the pentapeptide have been identified that make a significant contribution to its stability. It has been shown that the use of such combinations reduces the amount of data required to obtain a reliable prediction of pentapeptide stability.
期刊介绍：
Automation and Remote Control is one of the first journals on control theory. The scope of the journal is control theory problems and applications. The journal publishes reviews, original articles, and short communications (deterministic, stochastic, adaptive, and robust formulations) and its applications (computer control, components and instruments, process control, social and economy control, etc.).
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