Evaluation of Factors Contributing to Diagnosis of Crohn's Disease in the Face of Increasing Trend in Pakistan.

IF 1.8 Q3 GASTROENTEROLOGY & HEPATOLOGY Crohn's & Colitis 360 Pub Date : 2024-03-22 eCollection Date: 2024-01-01 DOI:10.1093/crocol/otae015
Tayyab Saeed Akhtar, Bilal Ashraf, Kanza Zahid, Sameen Abbas, Anosh Sana, Abdul Rauf Khan, Faiqa Ijaz, Faisal Riaz
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Abstract

Background: Crohn's disease (CD) is characterized by granulomatous inflammation of the digestive tract. Diagnosing CD involves assessing clinical symptoms, radiological and endoscopic findings, and histopathological evidence. Although previously considered a disease in developed countries, CD is increasing in developing nations, but challenges exist in diagnosing CD promptly. This study aims to report diagnostic parameters for early and correct CD diagnosis in Pakistan.

Methodology: A retrospective analysis from June 2016 to August 2023 of 22 CD patients was done, by data from medical records, questionnaires completed at diagnosis, and telephonic interviews. Baseline demographic and clinical characteristics were assessed, and patients were categorized using the Montreal classification.

Results: CD was diagnosed in 22 patients, with a 1:1 male-to-female ratio with a mean age of 33 years (range 15-55 years). Symptoms at presentation included abdominal pain (95.5%), watery diarrhea (86.4%), fever (31.8%), rectal bleeding (54.5%), and weight loss (81.8%) with 68% having symptoms for over 12 months before diagnosis. Disease characteristics were diverse, with various patterns of involvement and histopathological findings.

Conclusions: In resource-limited countries like Pakistan, the timely diagnosis of CD presents a significant healthcare challenge. Therefore, it is necessary to tackle these complex problems by enhancing diagnostic capabilities, raising medical awareness, and improving access to healthcare resources.

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面对巴基斯坦克罗恩病日益增多的趋势,对导致克罗恩病诊断的因素进行评估。
背景:克罗恩病(CD)的特征是消化道肉芽肿性炎症。诊断克罗恩病需要评估临床症状、放射学和内窥镜检查结果以及组织病理学证据。虽然 CD 以前被认为是发达国家的一种疾病,但在发展中国家的发病率正在上升,但在及时诊断 CD 方面仍存在挑战。本研究旨在报告巴基斯坦早期正确诊断 CD 的诊断参数:通过病历数据、诊断时填写的问卷以及电话访谈,对 2016 年 6 月至 2023 年 8 月期间的 22 名 CD 患者进行了回顾性分析。对基线人口统计学和临床特征进行了评估,并采用蒙特利尔分类法对患者进行了分类:结果:22 名患者被确诊为 CD,男女比例为 1:1,平均年龄为 33 岁(15-55 岁不等)。发病时的症状包括腹痛(95.5%)、水样腹泻(86.4%)、发热(31.8%)、直肠出血(54.5%)和体重减轻(81.8%),其中 68% 的患者在确诊前已有 12 个月以上的症状。疾病特征多种多样,受累模式和组织病理学结果也各不相同:在巴基斯坦这样资源有限的国家,及时诊断 CD 是一项重大的医疗挑战。因此,有必要通过增强诊断能力、提高医疗意识和改善医疗资源的获取来解决这些复杂的问题。
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来源期刊
Crohn's & Colitis 360
Crohn's & Colitis 360 Medicine-Gastroenterology
CiteScore
2.50
自引率
0.00%
发文量
41
审稿时长
12 weeks
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