A. Wiraya, L. Fitriana, Triyanto, Yudi Ari Adi, Yuvita Andriani Kusumadewi, Sarah Khoirunnisa
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引用次数: 0
Abstract
Transmission of COVID-19 occurs either through living media, such as interaction with a sufferer, or nonliving objects contaminated with the virus. Recovering sufferers and disinfectant spraying prevent interaction between people and virus become the treatment to overcome it. In this research, we formulate a new mathematical model as a three-dimensional ordinary differential equation system representing an interaction between viruses attached in nonliving media, susceptible, and infected subpopulations, including the treatment to investigate its effect. Disease-free, sterile-media endemic, and two nonsterile media endemic equilibriums exist in the model. The nonexistence of sterile-media equilibria interpreting the nonendemic condition is achieved by crossing the branch point bifurcation of the equilibria point as the infected subpopulation recovery rate increases. Continuation of the limit cycle generated at a Hopf bifurcation point as susceptible-coronavirus interaction prevention rate and period increase trigger two saddle-node bifurcations and a branch point bifurcation of cycle. Stable symmetric cycles with decreasing amplitude that make the dynamic of subpopulation easier to control start to be gained at the branch point bifurcation of cycle between the two saddle-node bifurcation points as the prevention rate increases. Some chaotic attractors which describe a complex and unpredictable pattern of the dynamic in the population are also found at inclination flip bifurcation by a continuation of a homoclinic orbit generated near the Bogdanov-Takens bifurcation point as the prevention rate increases while the recovery rate decreases. Increasing the recovery and prevention rate along with avoiding an increase of the prevention rate while the recovery rate decreases becomes the treatment to optimize the effort in overcoming COVID-19 transmission.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.