Can we improve therapeutic compliance in cancer patients? report of a cross-sectional case series study in Morocco

Khadija Mokhtari, B. Hajji, Hanane El oualy, Hamid Madani
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Abstract

Therapeutic compliance (TC) refers to the compliance of a patient to the prescriptions and recommendations of a doctor. Patients with cancer often exhibit unsatisfactory TC. The objective of our study was to assess TC levels in cancer patients and identify predictors of poor compliance. We conducted a cross-sectional study in March 2023 at the oncology center, where the vast majority of medical activity is performed in the day hospital. TC was measured using a questionnaire or survey. Various parameters were analyzed to identify predictive factors of poor therapeutic compliance. Our study included 175 cancer patients with a mean age of 55 years. The study revealed that 85% exhibited good compliance (GC) as indicated by the confidence interval [8.500 ± 0.075], signifying patients who consistently adhered to their medication schedule. Conversely, 15% demonstrated poor compliance (PC), as indicated by the confidence interval [0.825 ± 0.750]. Compliance status was assessed by considering patients who adhered to the prescribed medication timing as good compliance (GC) and those who did not adhere as poor compliance (PC). The analysis of our study results indicated that poor therapeutic compliance was associated with low socioeconomic and educational levels. Therefore, it is important to utilize all available resources to improve therapeutic compliance. The majority of factors contributing to poor compliance can be mitigated through effective coordination between the patient and their support network.
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我们能否提高癌症患者的治疗依从性? 摩洛哥横断面病例系列研究报告
治疗依从性(TC)是指患者对医生处方和建议的依从性。癌症患者的治疗依从性往往不尽人意。我们的研究旨在评估癌症患者的治疗依从性水平,并确定不良依从性的预测因素。我们于 2023 年 3 月在肿瘤中心进行了一项横断面研究,该中心的绝大多数医疗活动都是在日间医院进行的。采用问卷或调查的方式测量了依从性。对各种参数进行了分析,以确定治疗依从性差的预测因素。我们的研究包括 175 名癌症患者,平均年龄 55 岁。研究显示,85%的患者表现出良好的依从性(GC),置信区间为[8.500 ± 0.075],这表明患者始终坚持按时服药。相反,15% 的患者依从性较差 (PC),可信区间为 [0.825 ± 0.750]。评估依从性状况时,将遵守规定用药时间的患者视为依从性良好(GC),不遵守规定用药时间的患者视为依从性差(PC)。我们的研究结果分析表明,治疗依从性差与社会经济和教育水平低有关。因此,利用所有可用资源提高治疗依从性非常重要。导致依从性差的大多数因素都可以通过患者及其支持网络之间的有效协调来缓解。
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