{"title":"Development of a wearable surface enhanced Raman scattering sensor chip based on silver nanowires for rapid detection of urea, lactate and pH in sweat","authors":"Cristiano D'andrea","doi":"10.1051/jeos/2024013","DOIUrl":null,"url":null,"abstract":"A wearable sweat sensor chip based on surface-enhanced Raman spectroscopy (SERS) is here presented. The plasmonic core of the chip, obtained by deposition of silver nanowires on a polytetrafluoroethylene (PTFE) porous membrane, permits the direct and label-free detection of urea and lactate at physiologic concentrations in combination with the pH measurement in the range between 5 and 9. Once integrated with commercial biocompatible and adhesive tape layers, the as produced SERS-active chip provides a low-cost, flexible and wearable sensing device for rapid and reliable human sweat analysis. The chip was finally tested on real sweat samples to estimate lactate and urea during medium-intense exertions.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":"6 1","pages":""},"PeriodicalIF":17.7000,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"4","ListUrlMain":"https://doi.org/10.1051/jeos/2024013","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A wearable sweat sensor chip based on surface-enhanced Raman spectroscopy (SERS) is here presented. The plasmonic core of the chip, obtained by deposition of silver nanowires on a polytetrafluoroethylene (PTFE) porous membrane, permits the direct and label-free detection of urea and lactate at physiologic concentrations in combination with the pH measurement in the range between 5 and 9. Once integrated with commercial biocompatible and adhesive tape layers, the as produced SERS-active chip provides a low-cost, flexible and wearable sensing device for rapid and reliable human sweat analysis. The chip was finally tested on real sweat samples to estimate lactate and urea during medium-intense exertions.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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