Surface-engineered Multimodal Magnetic Nanoparticles: Scope and Applications

IF 0.3 Q4 PHARMACOLOGY & PHARMACY Current Drug Therapy Pub Date : 2024-03-19 DOI:10.2174/0115748855284579240307063006
Ritika Singh, Manoj Kumar Mishra, Prasoon Pandey
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引用次数: 0

Abstract

Magnetic nanoparticles (MNPs) are one of the classes of nanoparticles that produce magnetic properties by manipulation using a magnetic field. These MNPs are currently used in the theranostics disease modification of surface properties of MNPs, achieved by surface engineering, which provides different applications, such as enhancing thermal and optical properties, biocompatibility, conductivity and also mechanical and chemical properties. Advancement in the technology leads to the development of MNPs. For this instance, surface coating is used at molecular and cellular levels. The uses of coating material are based on organic and inorganic molecules, including polymer, liposomes, micelles, metal oxide, gold-NPs etc. Using different coatings exhibits multifunction properties, and this helps reduce toxicity, helps in biomedical applications, maintains stability, restricts surface fouling, etc. This review provides an in-depth knowledge of surface-engineered magnetic nanoparticles (MNPs) according to recent developments.
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表面工程多模式磁性纳米粒子:范围和应用
磁性纳米粒子(Magnetic nanoparticles,MNPs)是通过磁场操作产生磁性的纳米粒子之一。目前,这些 MNPs 被用于治疗通过表面工程改变 MNPs 表面特性的疾病,从而提供不同的应用,如增强热和光学特性、生物相容性、导电性以及机械和化学特性。技术的进步促进了 MNPs 的发展。例如,在分子和细胞水平上使用表面涂层。涂层材料的用途基于有机和无机分子,包括聚合物、脂质体、胶束、金属氧化物、金-NPs 等。使用不同的涂层可显示出多种功能特性,这有助于降低毒性、帮助生物医学应用、保持稳定性、限制表面污垢等。本综述将根据最新进展深入介绍表面工程磁性纳米粒子(MNPs)。
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来源期刊
Current Drug Therapy
Current Drug Therapy PHARMACOLOGY & PHARMACY-
CiteScore
1.30
自引率
0.00%
发文量
50
期刊介绍: Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.
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