A case of grade 3 squamous cell carcinoma successfully treated with methotrexate

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-03-14 DOI:10.4081/dr.2024.9647
Giovanni Sarracco, Fabio Rinaldi, Francesco Cusano
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Abstract

Cutaneous squamous cell carcinoma (cSCC) is a nonmelanoma skin cancer whose lesions mostly arise on lightexposed sites. Patients with compromised immunity, Fitzpatrick I or II skin phototype, and previous burn scars or radiations are more at risk of developing it. The treatment of choice for cSCC is surgery; however nonsurgical options are generally reserved for patients who refuse a very invasive treatment or cannot tolerate a surgical procedure. We report a case of cSCC successfully treated with intralesional methotrexate.
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用甲氨蝶呤成功治疗 3 级鳞状细胞癌的病例
皮肤鳞状细胞癌(cSCC)是一种非黑色素瘤皮肤癌,其病变主要发生在暴露于光线的部位。免疫力低下、菲茨帕特里克I型或II型皮肤光型、曾有烧伤疤痕或放射线照射的患者更容易患上这种疾病。手术是治疗 cSCC 的首选方法,但非手术疗法通常只适用于拒绝接受创伤性治疗或不能耐受手术的患者。我们报告了一例使用鞘内甲氨蝶呤成功治疗 cSCC 的病例。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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