Jon Lykkegaard Andersen, Jakob Sidenius Johansen, E. Urbanska, P. Meldgaard, Peter Hjorth-Hansen, Charlotte Kristiansen, Miroslaw Stelmach, Eric Santoni-Rugiu, M. P. Ulhoi, Betina Højgaard, Morten Sall Jensen, A. B. Dydensborg, C. Dünweber, K. H. Hansen
{"title":"Lung cancer patients with anaplastic lymphoma kinase rearrangement lose affiliation with labor market at diagnosis","authors":"Jon Lykkegaard Andersen, Jakob Sidenius Johansen, E. Urbanska, P. Meldgaard, Peter Hjorth-Hansen, Charlotte Kristiansen, Miroslaw Stelmach, Eric Santoni-Rugiu, M. P. Ulhoi, Betina Højgaard, Morten Sall Jensen, A. B. Dydensborg, C. Dünweber, K. H. Hansen","doi":"10.2217/lmt-2023-0013","DOIUrl":null,"url":null,"abstract":"Aim: The main purpose of the present study was to investigate the labor market affiliation of ALK+ NSCLC patients in long-term treatment as well as overall survival and incidence/prevalence. Materials & methods: Nationwide retrospective study of all patients with ALK+ NSCLC in Denmark diagnosed between 2012 and 2018. Results: During the study period ALK+ NSCLC patients had a median overall survival of 44.0 months and a 7.8-fold increase in disease prevalence. Six months prior to diagnosis, 81% of ALK+ NSCLC patients ≤60 years of age were employed. At the end of the 18-month follow-up period, 36% were employed. Conclusion: ALK+ NSCLC patients have prolonged survival following diagnosis, but a large fraction of patients lose affiliation with the labor market.","PeriodicalId":0,"journal":{"name":"","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/lmt-2023-0013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: The main purpose of the present study was to investigate the labor market affiliation of ALK+ NSCLC patients in long-term treatment as well as overall survival and incidence/prevalence. Materials & methods: Nationwide retrospective study of all patients with ALK+ NSCLC in Denmark diagnosed between 2012 and 2018. Results: During the study period ALK+ NSCLC patients had a median overall survival of 44.0 months and a 7.8-fold increase in disease prevalence. Six months prior to diagnosis, 81% of ALK+ NSCLC patients ≤60 years of age were employed. At the end of the 18-month follow-up period, 36% were employed. Conclusion: ALK+ NSCLC patients have prolonged survival following diagnosis, but a large fraction of patients lose affiliation with the labor market.