Colorectal cancer prediction via histopathology segmentation using DC-GAN and VAE-GAN

Abstract

Colorectal cancer ranks as the third most common form of cancer in the United States. The Centres of Disease Control and Prevention report that males and individuals assigned male at birth (AMAB) have a slightly higher incidence of colon cancer than females and those assigned female at birth (AFAB) Black humans are more likely than other ethnic groups or races to develop colon cancer. Early detection of suspicious tissues can improve a person's life for 3-4 years. In this project, we use the EBHI-seg dataset. This study explores a technique called Generative Adversarial Networks (GAN) that can be utilized for data augmentation colorectal cancer histopathology Image Segmentation. Specifically, we compare the effectiveness of two GAN models, namely the deep convolutional GAN (DC-GAN) and the Variational autoencoder GAN (VAE-GAN), in generating realistic synthetic images for training a neural network model for cancer prediction. Our findings suggest that DC-GAN outperforms VAE-GAN in generating high-quality synthetic images and improving the neural network model. These results highlight the possibility of GAN-based data augmentation to enhance machine learning models’ performance in medical image analysis tasks. The result shows DC-GAN outperformed VAE-GAN.