Conformable Fractional-Order Modeling and Analysis of HIV/AIDS Transmission Dynamics

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-03-12 DOI:10.1155/2024/1958622
Esam Y. Salah, Bahusaheb Sontakke, Mohammed S Abdo, W. Shatanawi, K. Abodayeh, M. D. Albalwi
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Abstract

The mathematical model of the dynamics of HIV/AIDS infection transmission is developed by adding the set of infected but noninfectious persons, using a conformable fractional derivative in the Liouville–Caputo sense. Some fixed point theorems are applied to this model to investigate the existence and uniqueness of the solutions. It is determined what the system’s fundamental reproduction number R0 is. The disease-free equilibrium displays the model’s stability and the local stability around the equilibrium. The study also examined the effects of different biological features on the system through numerical simulations using the Adams–Moulton approach. Additionally, varied values of fractional orders are simulated numerically, demonstrating that the results generated by the conformable fractional derivative-based model are more physiologically plausible than integer-order derivatives.
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艾滋病毒/艾滋病传播动态的可变分数阶建模与分析
利用 Liouville-Caputo 意义上的保形分数导数,通过添加感染但未感染的人群集合,建立了艾滋病毒/艾滋病感染传播动态数学模型。一些定点定理被应用于该模型,以研究解的存在性和唯一性。确定了系统的基本繁殖数 R0。无病平衡显示了模型的稳定性和平衡点附近的局部稳定性。研究还通过使用亚当斯-莫尔顿方法进行数值模拟,检验了不同生物特征对系统的影响。此外,还对不同的分数阶数值进行了数值模拟,结果表明,与整数阶导数相比,基于顺应分数导数的模型生成的结果在生理上更加合理。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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