Clinical and economic analysis of the application of the method of three-dimensional reconstruction of lung tissue in the practice of tuberculosis institution

Aleksey G. Naumov, Alexander S. Shprykov, Natalya Yu. Borodina
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Abstract

Background. The use of clinical and economic analysis in practical healthcare allows for a more rational use of the resources allocated by the state and contributes to the achievement of optimal indicators in terms of the quality of disease identification and the effectiveness of its treatment. Aim. To conduct a clinical and economic analysis of the prospects for introducing the 3D lung reconstruction method into tuberculosis practice, which is used to correct the level of adherence, reduce the severity of symptoms of anxiety and depression, and increase the effectiveness of chemotherapy. Materials and methods. In this scientific work, the results of treatment (more than 90 people) of newly diagnosed patients with destructive pulmonary tuberculosis, which were observed in the Nizhny Novgorod Regional Clinical Tuberculosis Dispensary, were used. The patients were divided into two groups. For the 1st group of patients, tactile lung models were made, among them a questionnaire was conducted using the MMAS-4 questionnaire and the HADS scale. For patients of the 2nd group, lung models were not made, and no survey was conducted. Each group was assessed the effectiveness of chemotherapy. Clinical and economic analysis of the cost of introducing the method of three-dimensional lung reconstruction into tuberculosis practice was carried out on the basis of two evaluation criteria «cost – effectiveness» and «cost-effectiveness increment» with additional mathematical calculations of the necessary indicators. The results obtained were compared with the existing known method of increasing adherence to tuberculosis treatment - the issuance of food packages. Results. Based on the results of the study, it was proved that the use of tactile models of the lungs in phthisiatric practice is more than 8 times cheaper than the method of issuing food kits with, in fact, comparable results of treatment effectiveness. If there is a need to increase the effectiveness of the treatment of tuberculosis patients by increasing the subsidy of food packages, the cost of one additional percent of efficiency is not economically viable. Conclusion. The clinical and economic analysis of the prospects for introducing the method of three-dimensional lung reconstruction into phthisiatric practice presented in the paper looks promising, which is confirmed by the performed mathematical calculations and comparisons, and can be recommended for use in the routine practice of phthisiatricians to correct the level of adherence of tuberculosis patients to chemotherapy, reduce the severity symptoms of anxiety and depression, as well as an increase in the effectiveness of treatment.
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肺组织三维重建方法在结核病机构实践中的临床和经济应用分析
背景。在实际医疗保健中使用临床和经济分析,可以更合理地使用国家分配的资源,并有助于在疾病识别质量和治疗效果方面实现最佳指标。目的对肺结核实践中引入三维肺重建方法的前景进行临床和经济分析,该方法用于纠正患者的依从性水平,降低焦虑和抑郁症状的严重程度,提高化疗效果。材料与方法。在这项科研工作中,使用了在下诺夫哥罗德地区临床结核病医院观察到的新诊断的破坏性肺结核患者(90 多人)的治疗结果。患者被分为两组。第一组患者制作了肺部触觉模型,并使用 MMAS-4 问卷和 HADS 量表对他们进行了问卷调查。第二组患者未制作肺部模型,也未进行问卷调查。对每组患者的化疗效果进行了评估。根据 "成本效益 "和 "成本效益增量 "两个评估标准,并对必要的指标进行了额外的数学计算,对在肺结核治疗中引入三维肺重建方法的成本进行了临床和经济分析。所得结果与现有的提高结核病治疗依从性的已知方法--发放食品包--进行了比较。结果。根据研究结果证明,在治疗过程中使用肺部触觉模型比发放食品包的方法便宜 8 倍以上,而实际上治疗效果相当。如果需要通过增加食品包的补贴来提高肺结核病人的治疗效果,那么增加百分之一的效率成本在经济上是不可行的。结论。本文对将肺部三维重建方法引入结核病治疗的前景进行了临床和经济分析,并通过数学计算和比较证实了这一点,建议在结核病医生的日常工作中使用该方法,以纠正结核病患者对化疗的依从性,减轻焦虑和抑郁症状的严重程度,并提高治疗效果。
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