Body Mass Index and Thyroid Function Tests in Male Adults in Mosul City

Ayman M. Taher, Hazim A. Mohammed
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Abstract

The relationship between thyroid gland and body mass index (BMI) is a subject of growing interest. Thyroid hormones' impact on metabolism directly affects energy expenditure which is in turn affect weight balance. Subjects and Method: This study occurred in Mosul city in the north of Iraq, between December 2022 - June 2023, and it comprised one hundred adult males ranging in age from 20 - 60 years. Participants had to be apparently healthy men with appropriate thyroid functions, according to the inclusion criteria. Individuals who used specific medicines known for altering thyroid functions were excluded, those who have positive anti-thyroid peroxidase antibodies (ATPO), a personal or familial history of thyroid diseases, and medical illnesses such as hypertension, diabetes, and cardiac, renal, and liver diseases. The thyroid parameters that’s measured to the subjects were triiodothyronine (FT3), thyroxine (FT4) using immuno-enzymatic competitive assays and Thyroid stimulating hormone (TSH) by two-site immuno-enzymatic (sandwich) method. Results: found no significant relationships between BMI and other thyroid function FT3 no significant increase TSH, on the contrary increased across BMI classes, moreover FT4 decreased.  Conclusion: this work showed that the thyroid function of the different BMI groups under investigation showed no significant change.
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摩苏尔市男性成年人的体重指数和甲状腺功能测试
甲状腺与体重指数(BMI)之间的关系是一个越来越受关注的话题。甲状腺激素对新陈代谢的影响会直接影响能量消耗,而能量消耗又会影响体重平衡。研究对象和方法:本研究于 2022 年 12 月至 2023 年 6 月期间在伊拉克北部摩苏尔市进行,由 100 名年龄在 20-60 岁之间的成年男性组成。根据纳入标准,参与者必须是表面健康、甲状腺功能正常的男性。排除使用已知会改变甲状腺功能的特定药物者、抗甲状腺过氧化物酶抗体(ATPO)阳性者、有甲状腺疾病个人或家族史者,以及患有高血压、糖尿病、心脏病、肾病和肝病等内科疾病者。对受试者进行的甲状腺参数测量包括:采用免疫酶竞争法检测三碘甲状腺原氨酸(FT3)和甲状腺素(FT4);采用双位免疫酶法(夹心法)检测促甲状腺激素(TSH)。结果:发现体重指数与其他甲状腺功能之间没有明显的关系,FT3 没有明显增加,相反,促甲状腺激素在不同体重指数等级中都有所增加,而且 FT4 有所下降。 结论:这项工作表明,所调查的不同 BMI 组的甲状腺功能没有明显变化。
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