{"title":"Development of a Smartphone-linked Optical Biosensing System for Point-of-care Testing Applications","authors":"Miku Sarubo, Yuka Numazaki, Hiroyuki Kudo","doi":"10.18494/sam4851","DOIUrl":null,"url":null,"abstract":"We report a miniaturized batteryless colorimetric biosensing system for measuring saliva components. Our system utilizes a CMOS image sensor and an LED light source embedded in smartphones as a part of the optical system. We measured the concentration of chemical substances by observing color changes of the coloring reagent DA-64, which is specific for hydrogen peroxide. The concentration calculated from the RGB scores of colorimetric images showed strong correlations ( r > 0.95) with the concentrations of the samples. This result shows the possibility of biochemical measurements using miniaturized biosensing systems to determine physiological conditions.","PeriodicalId":22154,"journal":{"name":"Sensors and Materials","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sensors and Materials","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.18494/sam4851","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"INSTRUMENTS & INSTRUMENTATION","Score":null,"Total":0}
引用次数: 0
Abstract
We report a miniaturized batteryless colorimetric biosensing system for measuring saliva components. Our system utilizes a CMOS image sensor and an LED light source embedded in smartphones as a part of the optical system. We measured the concentration of chemical substances by observing color changes of the coloring reagent DA-64, which is specific for hydrogen peroxide. The concentration calculated from the RGB scores of colorimetric images showed strong correlations ( r > 0.95) with the concentrations of the samples. This result shows the possibility of biochemical measurements using miniaturized biosensing systems to determine physiological conditions.
期刊介绍:
Sensors and Materials is designed to provide a forum for people working in the multidisciplinary fields of sensing technology, and publishes contributions describing original work in the experimental and theoretical fields, aimed at understanding sensing technology, related materials, associated phenomena, and applied systems. Expository review papers and short notes are also acceptable.