DETERMINING THE DEMOGRAPHIC PATTERNS OF DRUG-RESISTANT AND DRUG-SUSCEPTIBLE TUBERCULOSIS IN KPK, PAKISTAN THROUGH A RETROSPECTIVE SURVEY

Urooj Ahmad, Anab Arshad, Sara Jadoon, Shahana Saba Salih, Hafsa Ahmed, Samreen Saifullah, Huma Nayab, Sara Safi
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Abstract

Objectives: The objective of this research was to find out the demographic characteristics of drug-susceptible and drug-resistant Tuberculosis in Khyber Pakhtunkhwa, Pakistan. Material and Methods: A retrospective survey was conducted on data from the TB Control Program Khyber Pakhtunkhwa recorded between 1st January 2021 to 3rd June 2022. 7 sentinel sites and 5 Programmatic Management of Drug-resistant Tuberculosis sites report the data to the TB control program. The data was entered into Excel and analyzed through frequency tables, histograms, and bar charts. Results: A total of 39,210 Tuberculosis cases were reported to TB control program KPK from 1st January 2021 to 3rd June 2022; 38,723 were drug-susceptible while 487 were drug-resistant TB cases. The highest percentage of TB was found in the age group 15-24 years. Males were more affected than females with drug-susceptible TB. In contrast, drug-resistant TB was affecting females more than males.  58% of cases were reported in the public sector while 42% cases in the private sector. The households of only 2,412 (6.22%) patients of drug-susceptible Tuberculosis were screened out of 38,723 patients. In 2815 Tuberculosis patients screened for HIV, 4 drug-susceptible and 5 drug-resistant cases were positive for HIV. 8.41% of drug-resistant TB patients were diabetic. Conclusion: The frequency of TB cases is high in Khyber Pakhtunkhwa, especially among 15-24-year-olds. Household contact screening is inadequate in Khyber Pakhtunkhwa. There is a high percentage of coexisting drug-resistant TB and diabetes. Keywords: Drug susceptible TB, Drug-resistant TB, HIV co-infection, Household contact.  
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通过回顾性调查确定巴基斯坦 KPK 地区耐药性和药敏性结核病的人口模式
研究目的本研究旨在了解巴基斯坦开伯尔-普赫图赫瓦省易感和耐药结核病的人口统计学特征:对开伯尔-普赫图赫瓦省结核病控制项目在 2021 年 1 月 1 日至 2022 年 6 月 3 日期间记录的数据进行了回顾性调查。7 个哨点和 5 个耐药结核病计划管理站点向结核病控制计划报告数据。数据被输入 Excel,并通过频率表、柱状图和条形图进行分析:从 2021 年 1 月 1 日到 2022 年 6 月 3 日,肯塔基州结核病控制项目共收到 39210 例结核病报告,其中 38723 例为药物敏感型结核病,487 例为耐药型结核病。15-24 岁年龄组的结核病发病率最高。男性比女性更容易感染药物敏感型肺结核。相比之下,耐药性结核病对女性的影响大于男性。 据报告,58%的病例发生在公共部门,42%的病例发生在私营部门。在 38 723 名肺结核患者中,只有 2 412 名(6.22%)患者的家庭接受了筛查。在接受艾滋病毒筛查的 2815 名肺结核病人中,有 4 例药物敏感型和 5 例耐药型肺结核病人对艾滋病毒呈阳性反应。8.41%的耐药肺结核病人患有糖尿病:结论:开伯尔-普赫图赫瓦省的肺结核发病率很高,尤其是在 15-24 岁的人群中。开伯尔-普赫图赫瓦省对家庭接触者的筛查不足。同时患有耐药结核病和糖尿病的比例很高:易感结核病 耐药性结核病 艾滋病毒合并感染 家庭接触者
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