OUTCOME OF EARLY TRANSABDOMINAL SUPRAPUBIC REPAIR OF VESICOVAGINAL FISTULA SECONDARY TO BENIGN GYNECOLOGICAL AND OBSTETRIC SURGERIES

Hazrat ullah, Nasir Khan, Mahjabina S. Ghayur, Ahsan Rafi, Ishtia ur Rehman, Yasir Hakim
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Abstract

Objectives: To determine the effectiveness of early operative management of patients with Vesicovaginal fistula (VVF) secondary to benign gynecological surgeries. Material and methods: It is a descriptive case series of 70 patients selected from August 2018 to Oct 2022. All patients meeting inclusion criteria had routine lab investigations, imaging, cystoscopy, and vaginoscopy. The suprapubic approach described by O’Conor et al; was used. All surgeries were performed between the 4th and 6th weeks after the onset of the fistula to allow some time for tissue healing. All patients were followed after 2 weeks; a cystogram was performed to document fistula closure followed by removal of Foleys catheter. A second follow-up was at 3 months, patients were assessed with patient global impression of improvement score (PGI-I) for improvement in symptoms. Results: The mean age of the patients was 40.6 ± 10.2 years. 14(19.7%) patients were primipara while 56 (78.9%) patients were multipara. The mean fistula size was 11.5 ± 4.5mm. Supra-trigonal fistulas were more common than trigonal fistulas 43(60.6%) vs 27(38%). Hysterectomy (including cesarean hysterectomy and simple hysterectomy) was the commonest cause of VVF followed by cesarean section and difficult labor 33(46.5% vs 21(29.6) vs 12(16.9%). The overall mean operative time was 125.3 ± 10.7 minutes. The mean hospital stay was 3.8 ± 0.8 days. The fistula was successfully closed in 64 (90.1%) patients while 6 (9.9%) patients had failed surgery. The small-size fistulas (5-10mm) had a higher success rate of closure than larger fistulas (11-20mm) with statistical significance (p=0.02). Over 63 (90 %) patients responded PGI score below 3 with much improvement in symptoms. Conclusion: Our results show that early operative management of VVF secondary to benign gynecological and obstetric surgeries is feasible and effective. It also improves the symptoms of patients with PGI-I score. KEYWORDS: Vesicovaginal fistula (VVF), early repair, hysterectomy.
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妇产科良性手术继发膀胱阴道瘘的早期经腹耻骨上修补术的疗效
目的确定妇科良性手术继发膀胱阴道瘘(VVF)患者早期手术治疗的有效性:这是一个描述性病例系列,选取了 2018 年 8 月至 2022 年 10 月期间的 70 例患者。所有符合纳入标准的患者均进行了常规实验室检查、影像学检查、膀胱镜检查和阴道镜检查。采用O'Conor等人描述的耻骨上入路。所有手术均在瘘管出现后的第 4 至第 6 周进行,以便为组织愈合留出一定时间。2 周后对所有患者进行随访;进行膀胱造影以记录瘘管闭合情况,然后拔除 Foleys 导管。第二次随访是在 3 个月后,用患者总体改善印象评分(PGI-I)评估患者的症状改善情况:患者的平均年龄为 40.6 ± 10.2 岁。14名(19.7%)患者为初产妇,56名(78.9%)患者为多产妇。瘘管的平均大小为 11.5 ± 4.5 毫米。上三叉瘘比三叉瘘更常见,分别为 43(60.6%)对 27(38%)。子宫切除术(包括剖宫产子宫切除术和单纯子宫切除术)是导致 VVF 的最常见原因,其次是剖宫产和难产 33(46.5%) vs 21(29.6) vs 12(16.9%)。总平均手术时间为 125.3 ± 10.7 分钟。平均住院时间为 3.8 ± 0.8 天。64例(90.1%)患者的瘘管成功闭合,6例(9.9%)患者手术失败。小尺寸瘘管(5-10 毫米)的闭合成功率高于大尺寸瘘管(11-20 毫米),差异有统计学意义(P=0.02)。超过 63 名(90%)患者的 PGI 评分低于 3 分,症状大为改善:我们的研究结果表明,对继发于良性妇产科手术的 VVF 进行早期手术治疗是可行且有效的。关键词:膀胱阴道瘘(VVF)、早期修复、子宫切除术。
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