Anatomical-functional state of surface lymphatic system of lower extremities in chronic vein diseases according to fluorescence lymphograph

Kh. A. Abduvosidov, S. M. Chudnykh, V. G. Shestakova, A. G. Alekseev, M. M. Kokoev, N. S. Kozlov, G. M. Korolyuk
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Abstract

Despite the large arsenal of diagnostic methods for studying the lymphatic system, there are isolated works on its morpho-functional state in chronic venous insufluciency. The purpose of the study was to study the anatomical and physiological state of the surface lymphatic system of the lower extremities in persons with different clinical classes of chronic vein diseases using fluorescence lifography. The study was conducted in 105 patients divided into six groups according to the clinical class of chronic diseases of the veins of the lower extremities according to the CEAP classiffication. We used fluorescent lymphography using sodium fluorescein to study the anatomical and functional capabilities of the lymphotone. The study revealed that morphofunctional changes in superficial lymphatic vessels in chronic lower extremity vein diseases depend on venous system decompensation. With an increase in the clinical class of chronic diseases of the veins of the lower extremities, the rate of lymph flow through the superficial lymphatic vessels is statistically significantly reduced. At the same time, the antegrade lymph cell is completely absent in С5-С6, with the appearance of retrograde outflow and discharge of the lymph into the deep lymph vessels. Thus, the progression of chronic venous insufficiency leads to proportional progression of morphofunctional changes in the superficial lymphatic system, which leads to the formation of lymphovenous insufficiency.
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荧光淋巴管图显示慢性静脉疾病患者下肢表面淋巴系统的解剖功能状态
尽管研究淋巴系统的诊断方法种类繁多,但有关慢性静脉功能不全患者淋巴系统形态和功能状态的研究却鲜有问世。本研究的目的是利用荧光生命图谱研究不同临床级别的慢性静脉疾病患者下肢表面淋巴系统的解剖和生理状态。研究根据 CEAP 分级,按照下肢静脉慢性疾病的临床分级将 105 名患者分为六组。我们使用荧光素钠荧光淋巴造影来研究淋巴管的解剖和功能能力。研究显示,慢性下肢静脉疾病患者浅表淋巴管的形态功能变化取决于静脉系统的失代偿。据统计,随着下肢静脉慢性疾病临床分级的增加,通过浅表淋巴管的淋巴流量明显减少。同时,在С5-С6中,前行淋巴细胞完全消失,出现逆行流出,淋巴排入深层淋巴管。因此,慢性静脉功能不全的进展会导致浅表淋巴系统形态功能变化的成比例进展,从而形成淋巴-静脉功能不全。
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来源期刊
Biomedical Photonics
Biomedical Photonics Medicine-Surgery
CiteScore
1.80
自引率
0.00%
发文量
19
审稿时长
8 weeks
期刊介绍: The main goal of the journal – to promote the development of Russian biomedical photonics and implementation of its advances into medical practice. The primary objectives: - Presentation of up-to-date results of scientific and in research and scientific and practical (clinical and experimental) activity in the field of biomedical photonics. - Development of united Russian media for integration of knowledge and experience of scientists and practitioners in this field. - Distribution of best practices in laser medicine to regions. - Keeping the clinicians informed about new methods and devices for laser medicine - Approval of investigations of Ph.D candidates and applicants.
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