Neo-onset myocardial infraction in patients undergoing coronary artery bypass graft with and without long cross clamp time.

Muhammad Ammar, Madeeha Ghafoor, Shahbaz Hussain, Ammar Azam, Syed Muhammad Bahar, Ali Bukhari, Yumna Zaheer
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Abstract

Objective: To compare the frequency of new onset perioperative myocardial infarction in patients undergoing coronary artery bypass graft with and without long cross clamp time. Study Design: Randomized Control Trial. Setting: Department of Cardiac Surgery at the CH. Muhammad Akram Teaching and Research, Lahore. Period: 10th Feb 2023 to 10th June 2023. Material & Methods: Patients were admitted through out-patient department one week prior to the operation and randomized to Group L (longer aortic cross-clamp time) and Group S (shorter time). Preoperative electrocardiogram was recorded for every patient. After surgery patients were shifted to intensive care unit. Development of perioperative myocardial infarction was the major outcome variable. Results: In our study, frequency of perioperative myocardial infarction in both groups was 7% in Group-L and 3% in Group-S with a p value was 0.19. Conclusion: In summary, our study sheds light on the notable difference in the frequency of perioperative myocardial infarction among patients undergoing CABG, particularly in relation to cross clamp time. While our findings present valuable insights, the necessity for further validation through multicenter trials with a larger sample size is evident.
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接受冠状动脉旁路移植术的患者在使用或不使用长交叉钳夹时间时新发心肌梗死。
目的比较接受冠状动脉搭桥术的患者在使用和不使用长交叉钳夹时间的情况下,围术期新发心肌梗死的频率。研究设计:随机对照试验。研究地点CH. Muhammad Akram 教学医院心脏外科。Muhammad Akram 教学与研究中心心脏外科,拉合尔。时间: 2023 年 2 月 10 日至 2023 年 6 月 10 日2023 年 2 月 10 日至 2023 年 6 月 10 日。材料与方法:患者在手术前一周通过门诊部入院,随机分为 L 组(主动脉瓣夹闭时间较长)和 S 组(时间较短)。记录每位患者的术前心电图。手术后,患者转入重症监护室。围手术期心肌梗死是主要的结果变量。结果:在我们的研究中,两组围手术期心肌梗死的发生率分别为:L 组 7%,S 组 3%,P 值为 0.19。结论总之,我们的研究揭示了接受 CABG 患者围术期心肌梗死发生率的显著差异,尤其是与交叉钳夹时间的关系。虽然我们的研究结果提供了有价值的见解,但显然有必要通过样本量更大的多中心试验来进一步验证。
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