Effectiveness, cost-effectiveness and return on investment of individual placement and support compared with traditional vocational rehabilitation for individuals with severe mental illness in the Netherlands: a nationwide implementation study

M. Vukadin, W. Zwinkels, F. Schaafsma, M. Spijkerman, Marloes de Graaf-Zijl, Philippe Delespaul, Jaap van Weeghel, Johanna Maria van Dongen, Johannes R Anema
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Abstract

To assess the effectiveness, cost-effectiveness and return on investment of individual placement and support (IPS) implemented through a reimbursement strategy on a nationwide scale compared with traditional vocational rehabilitation (TVR) regarding sustainable participation in competitive employment in individuals with severe mental illness receiving sickness or disability benefits.An observational study was conducted using administrative data regarding all Dutch individuals receiving sickness or disability benefits in the period 2012–2019. Exact matching and difference-in-difference fixed-effect estimations were performed to handle the non-randomised nature of the data. The matched sample consisted of 863 IPS and 16 466 TVR participants. The primary effect measure was the proportion of individuals having worked for at least 48 hours per month in competitive employment (ie, for 12 hours or more per week); the proportion of individuals having worked in competitive employment for at least 1 hour per month was also evaluated. Cost-effectiveness and return on investment were assessed from the societal perspective (intervention, sickness/disability benefit and healthcare costs) and payer perspective (sickness/disability benefit costs).IPS led to a statistically significant higher probability of being competitively employed for at least 12 hours per week of 3.7% points (95% CI 0.8% to 6.7%) to 7.5% points (95% CI 3.8% to 11.3%) and of being competitively employed for at least 1 hour per month of 4.7% points (95% CI 1.6% to 7.7%) to 8.9% points (95% CI 5.2 to 12.6%) from 6 to 36 months after starting the intervention. From the societal and payer perspective, IPS was—on average—less costly and more effective than TVR and return-on-investment estimates showed that IPS was—on average—cost saving (eg, societal perspective: ∆C: −364 (95% CI −3977 to 3249); ∆E: 0.104 (95% CI 0.046 to 0.164); benefit–cost ratio: 2.1 (95% CI −14.8 to 19.1)), but the uncertainty surrounding these estimates was large.IPS implemented through a reimbursement strategy on a nationwide scale is more effective and potentially cost-effective than TVR in people with severe mental illness receiving sickness or disability benefits. Based on these results, the implementation of IPS by a wide scale reimbursement strategy could be promoted to enhance sustainable participation in competitive employment in these individuals. Future economic evaluations should strive for a more robust sample size and a long follow-up period.
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荷兰严重精神疾病患者个人安置和支持与传统职业康复相比的效果、成本效益和投资回报:一项全国范围的实施研究
目的:与传统的职业康复(TVR)相比,在全国范围内通过补偿策略实施的个人安置和支持(IPS)在帮助领取疾病或残疾津贴的严重精神疾病患者持续参与竞争性就业方面的有效性、成本效益和投资回报。研究采用精确匹配和差分固定效应估算来处理数据的非随机性。匹配样本包括 863 名 IPS 参与者和 16 466 名 TVR 参与者。主要的效果衡量指标是每月在竞争性就业岗位上工作至少 48 小时(即每周工作 12 小时或以上)的人数比例;同时还评估了每月在竞争性就业岗位上工作至少 1 小时的人数比例。从社会角度(干预、疾病/残疾福利和医疗成本)和支付方角度(疾病/残疾福利成本)评估了成本效益和投资回报。在开始干预后的 6 至 36 个月期间,IPS 使每周至少竞争性就业 12 小时的概率在统计意义上大幅提高了 3.7% 点(95% CI 0.8% 至 6.7%)至 7.5% 点(95% CI 3.8% 至 11.3%),每月至少竞争性就业 1 小时的概率在统计意义上大幅提高了 4.7% 点(95% CI 1.6% 至 7.7%)至 8.9% 点(95% CI 5.2 至 12.6%)。从社会和支付方的角度来看,IPS 比 TVR 平均成本更低,效果更好,投资回报估算显示,IPS 平均节省成本(例如,社会角度:∆C:-在全国范围内通过报销策略实施的 IPS 比 TVR 更为有效,而且在接受疾病或残疾津贴的重性精神病患者中可能更具成本效益。基于这些结果,可以通过大范围的报销策略来促进 IPS 的实施,以提高这些人持续参与竞争性就业的能力。未来的经济评估应力求样本量更大、随访时间更长。
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