Manifestaciones radiológicas del sarcoma sinovial

IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING RADIOLOGIA Pub Date : 2025-01-01 DOI:10.1016/j.rx.2024.01.005
A.M. Mazza Rapagna , P. Bas Alcolea , N. Martínez Arnau , M.L. Monreal , C. García Mur , A. Romeo Tris
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Abstract

Synovial sarcoma (SS) is a rare malignant neoplasm of the soft tissue adjacent to joints. It is the most commonly diagnosed non-rhabdomyosarcoma soft-tissue sarcoma (STS) in childhood (30%). Its most frequent location is the knee and ankle, and it is the most common STS to affect the foot. Unlike other STS, it has slow growth and an earlier age at diagnosis (adolescents and young adults), which is why many cases are initially misdiagnosed as benign processes. Magnetic resonance imaging (MRI) is key due to its characterisation capabilities as SS shares features with other STS. Definitive diagnosis is achieved through a pathological study that shows the pathognomonic translocation t(x;18)(p11;q11) with the fluorescence in situ hybridisation (FISH) technique. The objective of this article is to highlight the key characteristics that are useful for diagnosing SS, fundamentally through the use of radiological imaging techniques, as well as nuclear medicine and pathological studies, illustrated with cases diagnosed in our centre.

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滑膜肉瘤的放射学表现
摘要滑膜肉瘤(SS)是一种罕见的关节附近软组织恶性肿瘤。它是儿童期最常见的非横纹肌肉瘤软组织肉瘤(STS)(30%)。其最常见的位置是膝盖和脚踝,最常见的STS影响足部。与其他STS不同,它生长缓慢,诊断年龄较早(青少年和年轻人),这就是为什么许多病例最初被误诊为良性病变的原因。磁共振成像(MRI)是关键,因为它具有表征SS与其他STS共享特征的能力。通过荧光原位杂交(FISH)技术进行病理研究,发现病变易位t(x;18)(p11;q11),从而获得明确诊断。本文的目的是强调对诊断SS有用的关键特征,主要是通过使用放射成像技术,以及核医学和病理研究,并以我们中心诊断的病例为例。
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来源期刊
RADIOLOGIA
RADIOLOGIA RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.60
自引率
7.70%
发文量
105
审稿时长
52 days
期刊介绍: La mejor revista para conocer de primera mano los originales más relevantes en la especialidad y las revisiones, casos y notas clínicas de mayor interés profesional. Además es la Publicación Oficial de la Sociedad Española de Radiología Médica.
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