Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9), through an innovative virus-like particles (VLP)-based vaccine, enhance the antitumoral activity of a HER-2-VLP vaccine in a preclinical model of HER-2 positive breast cancer

F. Ruzzi, L. Scalambra, M. S. Semprini, O. M. Pittino, C. Cappello, S. Angelicola, A. Palladini, P. Nanni, C. Fougeroux, L. Goksøyr, A.F. Sander, P.L. Lollini
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通过基于病毒样颗粒 (VLP) 的创新疫苗,靶向 9 型枯草蛋白酶/kexin (PCSK9),提高 HER-2 阳性乳腺癌临床前模型中 HER-2-VLP 疫苗的抗肿瘤活性
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