Photon Counting Computed Tomography for Accurate Cribriform Plate (Lamina Cribrosa) Imaging in Adult Patients.

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Tomography Pub Date : 2024-03-08 DOI:10.3390/tomography10030031

Anna Klempka, Eduardo Ackermann, Sven Clausen, Christoph Groden

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Abstract

Detailed visualization of the cribriform plate is challenging due to its intricate structure. This study investigates how computed tomography (CT) with a novel photon counting (PC) detector enhance cribriform plate visualization compared to traditionally used energy-integrated detectors in patients. A total of 40 patients were included in a retrospective analysis, with half of them undergoing PC CT (Naeotom Alpha Siemens Healthineers, Forchheim, Germany) and the other half undergoing CT scans using an energy-integrated detector (Somatom Sensation 64, Siemens, Forchheim, Germany) in which the cribriform plate was visualized with a temporal bone protocol. Both groups of scans were evaluated for signal-to-noise ratio, radiation dose, the imaging quality of the whole scan overall, and, separately, the cribriform plate and the clarity of volume rendering reconstructions. Two independent observers conducted a qualitative analysis using a Likert scale. The results consistently demonstrated excellent imaging of the cribriform plate with the PC CT scanner, surpassing traditional technology. The visualization provided by PC CT allowed for precise anatomical assessment of the cribriform plate on multiplanar reconstructions and volume rendering imaging with reduced radiation dose (by approximately 50% per slice) and higher signal-to-noise ratio (by approximately 75%). In conclusion, photon-counting technology provides the possibility of better imaging of the cribriform plate in adult patients. This enhanced imaging could be utilized in skull base-associated pathologies, such as cerebrospinal fluid leaks, to visualize them more reliably for precise treatment.

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光子计数计算机断层扫描用于对成年患者的楔形板（楔形薄片）进行精确成像。

由于楔形骨板结构复杂，对其进行详细观察具有挑战性。本研究探讨了与传统使用的能量集成探测器相比，使用新型光子计数（PC）探测器的计算机断层扫描（CT）如何增强患者楔状板的可视化。一项回顾性分析共纳入了 40 名患者，其中一半接受了 PC CT（Naeotom Alpha Siemens Healthineers，德国福希海姆）扫描，另一半接受了使用能量集成探测器（Somatom Sensation 64，西门子，德国福希海姆）的 CT 扫描，其中楔形板通过颞骨方案进行了可视化。对两组扫描的信噪比、辐射剂量、整个扫描的成像质量进行了评估，并分别对楔形骨板和容积渲染重建的清晰度进行了评估。两名独立观察员采用李克特量表进行了定性分析。结果一致表明，PC CT 扫描仪对楔形板的成像效果极佳，超过了传统技术。PC CT 提供的可视化功能可在多平面重建和容积渲染成像中对楔形板进行精确的解剖评估，同时减少辐射剂量（每片减少约 50%）和提高信噪比（约 75%）。总之，光子计数技术可以更好地对成年患者的楔形板进行成像。这种增强成像可用于颅底相关病变，如脑脊液漏，以便更可靠地观察病变，进行精确治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tomography Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

2.70

自引率

10.50%

发文量

222

期刊介绍： TomographyTM publishes basic (technical and pre-clinical) and clinical scientific articles which involve the advancement of imaging technologies. Tomography encompasses studies that use single or multiple imaging modalities including for example CT, US, PET, SPECT, MR and hyperpolarization technologies, as well as optical modalities (i.e. bioluminescence, photoacoustic, endomicroscopy, fiber optic imaging and optical computed tomography) in basic sciences, engineering, preclinical and clinical medicine. Tomography also welcomes studies involving exploration and refinement of contrast mechanisms and image-derived metrics within and across modalities toward the development of novel imaging probes for image-based feedback and intervention. The use of imaging in biology and medicine provides unparalleled opportunities to noninvasively interrogate tissues to obtain real-time dynamic and quantitative information required for diagnosis and response to interventions and to follow evolving pathological conditions. As multi-modal studies and the complexities of imaging technologies themselves are ever increasing to provide advanced information to scientists and clinicians. Tomography provides a unique publication venue allowing investigators the opportunity to more precisely communicate integrated findings related to the diverse and heterogeneous features associated with underlying anatomical, physiological, functional, metabolic and molecular genetic activities of normal and diseased tissue. Thus Tomography publishes peer-reviewed articles which involve the broad use of imaging of any tissue and disease type including both preclinical and clinical investigations. In addition, hardware/software along with chemical and molecular probe advances are welcome as they are deemed to significantly contribute towards the long-term goal of improving the overall impact of imaging on scientific and clinical discovery.